NSAIDs and Bleeding in Periodontal Surgery

Aim: To evaluate and compare the clinical effects of ibuprofen and diclofenac sodium on bleeding during periodontal surgery. Materials and Methods: Thirteen medically healthy men and women of mean age 37.5±17.67 (mean age± standard deviation) were selected for the study. All the subjects were di...

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Bibliographic Details
Main Authors: Sanyuktha Shetty, Sharath K, Biju Thomas, Nitin Shetty, Arvind Shetty, Devanand Shetty
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2014-05-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/4344/7805_CE(Ra)_E(C)_F(AK)_PF1(AGAK)_PFA(AK)_PF2(PAG)_PF2(PN).pdf
Description
Summary:Aim: To evaluate and compare the clinical effects of ibuprofen and diclofenac sodium on bleeding during periodontal surgery. Materials and Methods: Thirteen medically healthy men and women of mean age 37.5±17.67 (mean age± standard deviation) were selected for the study. All the subjects were divided into three groups: control (C) and test groups (T1) and (T2). Each subject of T1 group and T2 group was given ibuprofen and diclofenac sodium respectively, prior to surgery. Bleeding times of patients were recorded prior to performance of periodontal flap surgical procedures. Results: It was found that there was increased bleeding time and increased peri-operative bleeding when ibuprofen and diclofenac sodium were taken prior to surgery and this was statistically significant. (2.5538 (T1), 1.8385 (T2) versus 1.2385 (C) minute, p= .001) (mean blood loss) and (62.0325 ± 9.0594 (T1), 51.082 ± 9.792 (T2) versus 37.4992 ± 5.99 (C) millilitre, p = .000). Conclusion: The findings of this study suggested that preoperative administration of ibuprofen and diclofenac sodium could increase bleeding time and peri - operative blood loss.
ISSN:2249-782X
0973-709X