hiPSC-Derived Cells as Models for Drug Discovery
More than 85% of pre-clinically tested drugs fail during clinical trials, which results in a long, inefficient and costly process, suggesting that animal models are often poor predictors of human biology [...]
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-08-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/16/8626 |
| id |
doaj-9f20f7343d1a44e5ad80507cf002472d |
|---|---|
| record_format |
Article |
| spelling |
doaj-9f20f7343d1a44e5ad80507cf002472d2021-08-26T13:52:07ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-08-01228626862610.3390/ijms22168626hiPSC-Derived Cells as Models for Drug DiscoveryRivka Ofir0BGU-iPSC Core Facility, The Regenerative Medicine & Stem Cell (RMSC) Research Center, Ben Gurion University of the Negev, Be’er Sheva 84105, IsraelMore than 85% of pre-clinically tested drugs fail during clinical trials, which results in a long, inefficient and costly process, suggesting that animal models are often poor predictors of human biology [...]https://www.mdpi.com/1422-0067/22/16/8626n/a |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Rivka Ofir |
| spellingShingle |
Rivka Ofir hiPSC-Derived Cells as Models for Drug Discovery International Journal of Molecular Sciences n/a |
| author_facet |
Rivka Ofir |
| author_sort |
Rivka Ofir |
| title |
hiPSC-Derived Cells as Models for Drug Discovery |
| title_short |
hiPSC-Derived Cells as Models for Drug Discovery |
| title_full |
hiPSC-Derived Cells as Models for Drug Discovery |
| title_fullStr |
hiPSC-Derived Cells as Models for Drug Discovery |
| title_full_unstemmed |
hiPSC-Derived Cells as Models for Drug Discovery |
| title_sort |
hipsc-derived cells as models for drug discovery |
| publisher |
MDPI AG |
| series |
International Journal of Molecular Sciences |
| issn |
1661-6596 1422-0067 |
| publishDate |
2021-08-01 |
| description |
More than 85% of pre-clinically tested drugs fail during clinical trials, which results in a long, inefficient and costly process, suggesting that animal models are often poor predictors of human biology [...] |
| topic |
n/a |
| url |
https://www.mdpi.com/1422-0067/22/16/8626 |
| work_keys_str_mv |
AT rivkaofir hipscderivedcellsasmodelsfordrugdiscovery |
| _version_ |
1721192728719523840 |