Corneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technology

Abstract Background The aim of this study was to evaluate corneal biomechanical properties in a population of healthy children in China using corneal visualization Scheimpflug technology (CST). Methods All children underwent complete bi-ocular examinations. CST provided intraocular pressure (IOP) an...

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Main Authors: Miao He, Hui Ding, Hong He, Chi Zhang, Liangping Liu, Xingwu Zhong
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Ophthalmology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12886-017-0463-x
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spelling doaj-9f2d968504ac4244ad52facdcb70172c2020-11-24T21:11:06ZengBMCBMC Ophthalmology1471-24152017-05-011711710.1186/s12886-017-0463-xCorneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technologyMiao He0Hui Ding1Hong He2Chi Zhang3Liangping Liu4Xingwu Zhong5Zhongshan Ophthalmic Center and State Key Laboratory of Ophthalmology, Sun Yat-sen UniversityHainan Eye Hospital, Zhongshan Ophthalmic Center, Sun Yat-sen UniversityHainan Eye Hospital, Zhongshan Ophthalmic Center, Sun Yat-sen UniversityZhongshan Ophthalmic Center and State Key Laboratory of Ophthalmology, Sun Yat-sen UniversityZhongshan Ophthalmic Center and State Key Laboratory of Ophthalmology, Sun Yat-sen UniversityZhongshan Ophthalmic Center and State Key Laboratory of Ophthalmology, Sun Yat-sen UniversityAbstract Background The aim of this study was to evaluate corneal biomechanical properties in a population of healthy children in China using corneal visualization Scheimpflug technology (CST). Methods All children underwent complete bi-ocular examinations. CST provided intraocular pressure (IOP) and corneal biomechanical parameters, including time, velocity, length and deformation amplitude at first applanation (A1T, A1V, A1L, A1DA), at second applanation (A2T, A2V, A2L, A2DA), highest concavity time (HCT), maximum deformation amplitude (MDA), peak distance (PD), and radius of curvature (RoC). Pearson correlation analysis was used to assess the impacts of demographic factors, central corneal thickness (CCT), spherical equivalent (SE), and IOP on corneal biomechanics. Results One hundred eight subjects (32 girls and 76 boys) with the mean age of 10.80 ± 4.13 years (range 4 to18 years) were included in the final analyses. The right and left eyes were highly symmetrical in SE (p = 0.082), IOP (p = 0.235), or CCT (p = 0.210). Mean A1T of the right eyes was 7.424 ± 0.340 ms; the left eyes 7.451 ± 0.365 ms. MDA was 0.993 ± 0.102 mm in the right eyes and 0.982 ± 0.100 mm in the left eyes. Mean HCT of the right eyes was 16.675 ± 0.502 ms; the left eyes 16.735 ± 0.555 ms. All CST parameters of both eye were remarkably symmetrical with the exception of A2L (p = 0.006), A1DA (p = 0.025). The majority of CST parameters of both eyes were significantly correlated with CCT and IOP (p < 0.05). However, age, SE, and sex exert little influence on the CST measurements. Conclusions This study found interocular symmetry in corneal biomechanics in healthy children eyes. Several CST biomechanical parameters in children are modified by CCT and IOP.http://link.springer.com/article/10.1186/s12886-017-0463-xCorvis STCorneal biomechanicsCorneal deformationSymmetryChineseChildren
collection DOAJ
language English
format Article
sources DOAJ
author Miao He
Hui Ding
Hong He
Chi Zhang
Liangping Liu
Xingwu Zhong
spellingShingle Miao He
Hui Ding
Hong He
Chi Zhang
Liangping Liu
Xingwu Zhong
Corneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technology
BMC Ophthalmology
Corvis ST
Corneal biomechanics
Corneal deformation
Symmetry
Chinese
Children
author_facet Miao He
Hui Ding
Hong He
Chi Zhang
Liangping Liu
Xingwu Zhong
author_sort Miao He
title Corneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technology
title_short Corneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technology
title_full Corneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technology
title_fullStr Corneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technology
title_full_unstemmed Corneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technology
title_sort corneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technology
publisher BMC
series BMC Ophthalmology
issn 1471-2415
publishDate 2017-05-01
description Abstract Background The aim of this study was to evaluate corneal biomechanical properties in a population of healthy children in China using corneal visualization Scheimpflug technology (CST). Methods All children underwent complete bi-ocular examinations. CST provided intraocular pressure (IOP) and corneal biomechanical parameters, including time, velocity, length and deformation amplitude at first applanation (A1T, A1V, A1L, A1DA), at second applanation (A2T, A2V, A2L, A2DA), highest concavity time (HCT), maximum deformation amplitude (MDA), peak distance (PD), and radius of curvature (RoC). Pearson correlation analysis was used to assess the impacts of demographic factors, central corneal thickness (CCT), spherical equivalent (SE), and IOP on corneal biomechanics. Results One hundred eight subjects (32 girls and 76 boys) with the mean age of 10.80 ± 4.13 years (range 4 to18 years) were included in the final analyses. The right and left eyes were highly symmetrical in SE (p = 0.082), IOP (p = 0.235), or CCT (p = 0.210). Mean A1T of the right eyes was 7.424 ± 0.340 ms; the left eyes 7.451 ± 0.365 ms. MDA was 0.993 ± 0.102 mm in the right eyes and 0.982 ± 0.100 mm in the left eyes. Mean HCT of the right eyes was 16.675 ± 0.502 ms; the left eyes 16.735 ± 0.555 ms. All CST parameters of both eye were remarkably symmetrical with the exception of A2L (p = 0.006), A1DA (p = 0.025). The majority of CST parameters of both eyes were significantly correlated with CCT and IOP (p < 0.05). However, age, SE, and sex exert little influence on the CST measurements. Conclusions This study found interocular symmetry in corneal biomechanics in healthy children eyes. Several CST biomechanical parameters in children are modified by CCT and IOP.
topic Corvis ST
Corneal biomechanics
Corneal deformation
Symmetry
Chinese
Children
url http://link.springer.com/article/10.1186/s12886-017-0463-x
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