Toxoplasma gondii Intravacuolar-Network-Associated Dense Granule Proteins Regulate Maturation of the Cyst Matrix and Cyst Wall

Toxoplasma gondii establishes chronic infection in humans by forming thick-walled cysts that persist in the brain. If host immunity wanes, cysts reactivate to cause severe, and often lethal, toxoplasmic encephalitis. There is no available therapy to eliminate cysts or to prevent their reactivation....

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Bibliographic Details
Main Authors: Rebekah B. Guevara, Barbara A. Fox, Alejandra Falla, David J. Bzik
Format: Article
Language:English
Published: American Society for Microbiology 2019-10-01
Series:mSphere
Subjects:
Online Access:https://doi.org/10.1128/mSphere.00487-19