VARIABILITY OF THE INFLUENZA A VIRUS
Aim. To investigate the mechanisms of variability of the influenza virus.Discussion. Influenza is one of the most significant problems facing the health care system. Human influenza causes a number of social and economic problems: mortality in high-risk groups, increasing in the load on personnel ag...
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doaj-9f3696e4e385440bbd028b9ee717d43d2021-07-28T21:17:36ZrusKamertonÛg Rossii: Èkologiâ, Razvitie1992-10982413-09582016-03-0111117017710.18470/1992-1098-2016-1-170-177814VARIABILITY OF THE INFLUENZA A VIRUSI. A. Sobolev0O. G. Kurskaya1K. A. Sharshov2E. A. Prokopyeva3A. Yu. Alekseev4A. A. Gadzhiev5A. M. Shestopalov6Research Institute of Experimental and Clinical MedicineResearch Institute of Experimental and Clinical MedicineResearch Institute of Experimental and Clinical MedicineResearch Institute of Experimental and Clinical MedicineResearch Institute of Experimental and Clinical MedicineDagestan State UniversityResearch Institute of Experimental and Clinical MedicineAim. To investigate the mechanisms of variability of the influenza virus.Discussion. Influenza is one of the most significant problems facing the health care system. Human influenza causes a number of social and economic problems: mortality in high-risk groups, increasing in the load on personnel agencies health and reduced manpower. Features of the influenza virus genome enable the pathogen to cause seasonal epidemics each year, despite the preventive measures (vaccination) and using of specific antiviral drugs.Conclusion. Variability of the influenza virus genome is provided by antigenic drift, antigenic shift and recombination. This mechanisms of the variability of influenza virus that allow to remain a highly contagious infectious agent able to infect a large number of host species and cause significant problems as a result of epidemics and pandemics.https://ecodag.elpub.ru/ugro/article/view/814influenza virusvariabilityantigenic driftantigenic shifthemagglutininneuraminidaseevolution |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
I. A. Sobolev O. G. Kurskaya K. A. Sharshov E. A. Prokopyeva A. Yu. Alekseev A. A. Gadzhiev A. M. Shestopalov |
spellingShingle |
I. A. Sobolev O. G. Kurskaya K. A. Sharshov E. A. Prokopyeva A. Yu. Alekseev A. A. Gadzhiev A. M. Shestopalov VARIABILITY OF THE INFLUENZA A VIRUS Ûg Rossii: Èkologiâ, Razvitie influenza virus variability antigenic drift antigenic shift hemagglutinin neuraminidase evolution |
author_facet |
I. A. Sobolev O. G. Kurskaya K. A. Sharshov E. A. Prokopyeva A. Yu. Alekseev A. A. Gadzhiev A. M. Shestopalov |
author_sort |
I. A. Sobolev |
title |
VARIABILITY OF THE INFLUENZA A VIRUS |
title_short |
VARIABILITY OF THE INFLUENZA A VIRUS |
title_full |
VARIABILITY OF THE INFLUENZA A VIRUS |
title_fullStr |
VARIABILITY OF THE INFLUENZA A VIRUS |
title_full_unstemmed |
VARIABILITY OF THE INFLUENZA A VIRUS |
title_sort |
variability of the influenza a virus |
publisher |
Kamerton |
series |
Ûg Rossii: Èkologiâ, Razvitie |
issn |
1992-1098 2413-0958 |
publishDate |
2016-03-01 |
description |
Aim. To investigate the mechanisms of variability of the influenza virus.Discussion. Influenza is one of the most significant problems facing the health care system. Human influenza causes a number of social and economic problems: mortality in high-risk groups, increasing in the load on personnel agencies health and reduced manpower. Features of the influenza virus genome enable the pathogen to cause seasonal epidemics each year, despite the preventive measures (vaccination) and using of specific antiviral drugs.Conclusion. Variability of the influenza virus genome is provided by antigenic drift, antigenic shift and recombination. This mechanisms of the variability of influenza virus that allow to remain a highly contagious infectious agent able to infect a large number of host species and cause significant problems as a result of epidemics and pandemics. |
topic |
influenza virus variability antigenic drift antigenic shift hemagglutinin neuraminidase evolution |
url |
https://ecodag.elpub.ru/ugro/article/view/814 |
work_keys_str_mv |
AT iasobolev variabilityoftheinfluenzaavirus AT ogkurskaya variabilityoftheinfluenzaavirus AT kasharshov variabilityoftheinfluenzaavirus AT eaprokopyeva variabilityoftheinfluenzaavirus AT ayualekseev variabilityoftheinfluenzaavirus AT aagadzhiev variabilityoftheinfluenzaavirus AT amshestopalov variabilityoftheinfluenzaavirus |
_version_ |
1721260932007460864 |