Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.

Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.

Epstein-Barr virus (EBV) is associated with human malignancies, especially those affecting the B cell compartment such as Burkitt lymphoma. The virally encoded homolog of the mammalian pro-survival protein Bcl-2, BHRF1 contributes to viral infectivity and lymphomagenesis. In addition to the pro-apop...

Full description

Bibliographic Details
Main Authors: Marc Kvansakul, Andrew H Wei, Jamie I Fletcher, Simon N Willis, Lin Chen, Andrew W Roberts, David C S Huang, Peter M Colman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3009601?pdf=render

Similar Items

Similar Items