Synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimp
Isatin (3a), isatin 3-carbohydrazone (4a), 5-spiro (isatin) 2-(N-acetyl hydrazino) 4-(N-acetyl)-2-1,3,4 oxadiazoline (5a), and 5-spiro (isatin) 2-hydrazino-2-1,3,4 oxadiazoline (6a) have been synthesized from unsubstituted oximinoacetanilide (2a). 4-Chlorooximinoacetanilide (2b), 5-chloroisatin (3...
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Bangladesh Pharmacological Society
2007-06-01
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| Series: | Bangladesh Journal of Pharmacology |
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| Online Access: | http://www.bdjpharmacol.com/journalbdps0201/020107.pdf |
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doaj-9f6e89147e52405ca719cba2218a8bd52020-11-24T20:42:44ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-007X1991-00882007-06-0121712Synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimpMd. Rabiul Islam and Mohammad MohsinIsatin (3a), isatin 3-carbohydrazone (4a), 5-spiro (isatin) 2-(N-acetyl hydrazino) 4-(N-acetyl)-2-1,3,4 oxadiazoline (5a), and 5-spiro (isatin) 2-hydrazino-2-1,3,4 oxadiazoline (6a) have been synthesized from unsubstituted oximinoacetanilide (2a). 4-Chlorooximinoacetanilide (2b), 5-chloroisatin (3b), 5-chloroisatin 3-carbohydrazone (4b) and 5-spiro (5-chloroisatin) 2-(N-acetyl hydrazino) 4-N-acetyl 2-1,3,4 oxadiazoline (5b) compounds have been synthesized from p-chloroaniline. The structures of the products have been characterized from spectral analysis and comparative cytotoxicity study of them was studied. www.bdjpharmacol.com/journalbdps0201/020107.pdfchloroisatincytotoxicityoxadiazoline |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Md. Rabiul Islam and Mohammad Mohsin |
| spellingShingle |
Md. Rabiul Islam and Mohammad Mohsin Synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimp Bangladesh Journal of Pharmacology chloroisatin cytotoxicity oxadiazoline |
| author_facet |
Md. Rabiul Islam and Mohammad Mohsin |
| author_sort |
Md. Rabiul Islam and Mohammad Mohsin |
| title |
Synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimp |
| title_short |
Synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimp |
| title_full |
Synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimp |
| title_fullStr |
Synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimp |
| title_full_unstemmed |
Synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimp |
| title_sort |
synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimp |
| publisher |
Bangladesh Pharmacological Society |
| series |
Bangladesh Journal of Pharmacology |
| issn |
1991-007X 1991-0088 |
| publishDate |
2007-06-01 |
| description |
Isatin (3a), isatin 3-carbohydrazone (4a), 5-spiro (isatin) 2-(N-acetyl hydrazino) 4-(N-acetyl)-2-1,3,4 oxadiazoline (5a), and 5-spiro (isatin) 2-hydrazino-2-1,3,4 oxadiazoline (6a) have been synthesized from unsubstituted oximinoacetanilide (2a). 4-Chlorooximinoacetanilide (2b), 5-chloroisatin (3b), 5-chloroisatin 3-carbohydrazone (4b) and 5-spiro (5-chloroisatin) 2-(N-acetyl hydrazino) 4-N-acetyl 2-1,3,4 oxadiazoline (5b) compounds have been synthesized from p-chloroaniline. The structures of the products have been characterized from spectral analysis and comparative cytotoxicity study of them was studied. |
| topic |
chloroisatin cytotoxicity oxadiazoline |
| url |
http://www.bdjpharmacol.com/journalbdps0201/020107.pdf |
| work_keys_str_mv |
AT mdrabiulislamandmohammadmohsin synthesisofisatin5chloroisatinandtheir2134oxadiazolinederivativesforcomparativecytotoxicitystudyonbrineshrimp |
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1716821975620386816 |