Patch clamp-assisted single neuron lipidomics

Abstract Our understanding of the physiological and pathological functions of brain lipids is limited by the inability to analyze these molecules at cellular resolution. Here, we present a method that enables the detection of lipids in identified single neurons from live mammalian brains. Neuronal c...

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Bibliographic Details
Main Authors: Collin B. Merrill, Abdul Basit, Andrea Armirotti, Yousheng Jia, Christine M. Gall, Gary Lynch, Daniele Piomelli
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05607-3