Silencing of Plasma Membrane Ca2+-ATPase Isoforms 2 and 3 Impairs Energy Metabolism in Differentiating PC12 Cells
A close link between Ca2+, ATP level, and neurogenesis is apparent; however, the molecular mechanisms of this relationship have not been completely elucidated. Transient elevations of cytosolic Ca2+ may boost ATP synthesis, but ATP is also consumed by ion pumps to maintain a low Ca2+ in cytosol. In...
Main Authors: | Tomasz Boczek, Malwina Lisek, Bozena Ferenc, Antoni Kowalski, Magdalena Wiktorska, Ludmila Zylinska |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2014/735106 |
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