Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study.
To investigate factors associated with ocular axial elongation and myopia progression during a 4-year follow-up in primary school children in Beijing.This school-based study included 382 grade-1 children at baseline in 2011 (age:6.3±0.4 years) with 305 (79.8%) returning for the follow-up examination...
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doaj-9fa63487ac534825a41ecf6e381a17402020-11-25T02:41:26ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01124e017592110.1371/journal.pone.0175921Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study.Yin GuoLi Juan LiuPing TangYan Yun LvYi FengLiang XuJost B JonasTo investigate factors associated with ocular axial elongation and myopia progression during a 4-year follow-up in primary school children in Beijing.This school-based study included 382 grade-1 children at baseline in 2011 (age:6.3±0.4 years) with 305 (79.8%) returning for the follow-up examination in 2015. At baseline and in yearly follow-up examinations, the children underwent a comprehensive eye examination including auto-refractometry, ocular biometry with measurement of axial length, and fundus photography. The parents underwent a standardized interview.During the study period, the mean axial length elongated by 1.15±0.56mm in boys and 1.10±0.63mm in girls. At baseline and at the end of follow-up, axial length was significantly (P<0.001) longer in boys, with no difference (P = 0.50) between genders in axial elongation. In multivariate analysis, greater axial elongation was associated (regression coefficient r2:0.15) with less time spent outdoors (P = 0.004; standardized coefficient beta: -0.22), more time spent indoors with studying (P = 0.02; beta: 0.18) and paternal myopia (P = 0.03; beta: 0.16). Larger increases in the axial length/anterior corneal curvature (AL/CC) ratio were associated (r2:0.09) with less time spent outdoors (PP = 0.003; beta: -0.22) and maternal myopia (PP = 0.02; beta: 0.18).Myopic axial elongation during a 4-year follow-up was associated with shorter time spent outdoors and longer time spent indoors studying and with parental myopia. Other factors such as level of paternal education, family income, gender and region of habitation were significantly associated with axial elongation and with myopia progression only in univariate analysis.http://europepmc.org/articles/PMC5407804?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yin Guo Li Juan Liu Ping Tang Yan Yun Lv Yi Feng Liang Xu Jost B Jonas |
spellingShingle |
Yin Guo Li Juan Liu Ping Tang Yan Yun Lv Yi Feng Liang Xu Jost B Jonas Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study. PLoS ONE |
author_facet |
Yin Guo Li Juan Liu Ping Tang Yan Yun Lv Yi Feng Liang Xu Jost B Jonas |
author_sort |
Yin Guo |
title |
Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study. |
title_short |
Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study. |
title_full |
Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study. |
title_fullStr |
Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study. |
title_full_unstemmed |
Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study. |
title_sort |
outdoor activity and myopia progression in 4-year follow-up of chinese primary school children: the beijing children eye study. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2017-01-01 |
description |
To investigate factors associated with ocular axial elongation and myopia progression during a 4-year follow-up in primary school children in Beijing.This school-based study included 382 grade-1 children at baseline in 2011 (age:6.3±0.4 years) with 305 (79.8%) returning for the follow-up examination in 2015. At baseline and in yearly follow-up examinations, the children underwent a comprehensive eye examination including auto-refractometry, ocular biometry with measurement of axial length, and fundus photography. The parents underwent a standardized interview.During the study period, the mean axial length elongated by 1.15±0.56mm in boys and 1.10±0.63mm in girls. At baseline and at the end of follow-up, axial length was significantly (P<0.001) longer in boys, with no difference (P = 0.50) between genders in axial elongation. In multivariate analysis, greater axial elongation was associated (regression coefficient r2:0.15) with less time spent outdoors (P = 0.004; standardized coefficient beta: -0.22), more time spent indoors with studying (P = 0.02; beta: 0.18) and paternal myopia (P = 0.03; beta: 0.16). Larger increases in the axial length/anterior corneal curvature (AL/CC) ratio were associated (r2:0.09) with less time spent outdoors (PP = 0.003; beta: -0.22) and maternal myopia (PP = 0.02; beta: 0.18).Myopic axial elongation during a 4-year follow-up was associated with shorter time spent outdoors and longer time spent indoors studying and with parental myopia. Other factors such as level of paternal education, family income, gender and region of habitation were significantly associated with axial elongation and with myopia progression only in univariate analysis. |
url |
http://europepmc.org/articles/PMC5407804?pdf=render |
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