Revisiting date and party hubs: novel approaches to role assignment in protein interaction networks.

The idea of "date" and "party" hubs has been influential in the study of protein-protein interaction networks. Date hubs display low co-expression with their partners, whilst party hubs have high co-expression. It was proposed that party hubs are local coordinators whereas date h...

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Bibliographic Details
Main Authors: Sumeet Agarwal, Charlotte M Deane, Mason A Porter, Nick S Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2887459?pdf=render