Back-Splicing Transcript Isoforms (Circular RNAs) Affect Biologically Relevant Pathways and Offer an Additional Layer of Information to Stratify NMIBC Patients

Back-Splicing Transcript Isoforms (Circular RNAs) Affect Biologically Relevant Pathways and Offer an Additional Layer of Information to Stratify NMIBC Patients

Circularized transcript isoforms due to back-splicing are increasingly being reported in different tissues types and pathological states including cancer. Since these circular RNAs (circRNAs) are more stable than linear messenger RNA their identification and profiling in tumor tissue could aid in st...

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Bibliographic Details
Main Authors: Anshita Goel, Douglas G. Ward, Naheema S. Gordon, Ben Abbotts, Maurice P. Zeegers, K. K. Cheng, Nicholas D. James, Richard T. Bryan, Roland Arnold
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
circular RNA
back-splicing
bladder cancer
tumor grade
NMIBC
biomarkers
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00812/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00812/full

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