The HMGB1 signaling pathway activates the inflammatory response in Schwann cells

The HMGB1 signaling pathway activates the inflammatory response in Schwann cells

Schwann cells are not only myelinating cells, but also function as immune cells and express numerous innate pattern recognition receptors, including the Toll-like receptors. Injury to peripheral nerves activates an inflammatory response in Schwann cells. However, it is unclear whether specific endog...

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Bibliographic Details
Main Authors: Li-li Man, Fan Liu, Ying-jie Wang, Hong-hua Song, Hong-bo Xu, Zi-wen Zhu, Qing Zhang, Yong-jun Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; peripheral nerve injury; sciatic nerve transection; Schwann cells; HMGB1; migration; inflammatory response; TLRs; peripheral nerves; DAMPs; cytokines; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=10;spage=1706;epage=1712;aulast=Man

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=10;spage=1706;epage=1712;aulast=Man

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