Microwave assisted synthesis of 4-quinolones and N,N′-diarylureas
4-Quinolinones are an important class of alkaloids, widely used as conventional drugs to treat various infectious diseases. In this study, we report the synthesis of 4-quinolones in one step, under microwave irradiation and with diphenyl ether as a solvent, using ethyl acetoacetate and electron rich...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2013-02-01
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Series: | Green Processing and Synthesis |
Subjects: | |
Online Access: | https://doi.org/10.1515/gps-2012-0083 |
Summary: | 4-Quinolinones are an important class of alkaloids, widely used as conventional drugs to treat various infectious diseases. In this study, we report the synthesis of 4-quinolones in one step, under microwave irradiation and with diphenyl ether as a solvent, using ethyl acetoacetate and electron rich anilines. When anilines containing alkyl or electron withdrawing substituents were employed, only N,N′-diarylureas were obtained in moderate to good yields. |
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ISSN: | 2191-9542 2191-9550 |