Reversible inactivation of the transcriptional function of P53 protein by farnesylation

Reversible inactivation of the transcriptional function of P53 protein by farnesylation

<p>Abstract</p> <p>Background</p> <p>The use of integrating viral vectors in Gene therapy clinical trials has pointed out the problem of the deleterous effect of the integration of the ectopic gene to the cellular genome and the safety of this strategy. We proposed here...

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Bibliographic Details
Main Authors: Berg Danièle, Casteignau Antoine, Pradines Anne, Tohfe Mustapha, Penary Marie, Couderc Bettina, Favre Gilles
Format: Article
Language:English
Published: BMC 2006-05-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/6/26

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http://www.biomedcentral.com/1472-6750/6/26

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