Protective effect of resveratrol against corticosterone-induced neurotoxicity in PC12 cells

Protective effect of resveratrol against corticosterone-induced neurotoxicity in PC12 cells

Resveratrol(RES) is a natural polyphenol which possesses an anti-depressant effect. However, the mechanisms of its anti-depressant effect remain unclear. The aim of the study is to investigate the potential mechanisms in the neuro-protective efficiency in the corticosterone-induced pheochromacytoma...

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Main Authors: Zhang Ye, He Yun, Deng Ning, Chen Yan, Huang Jiecong, Xie Wei
Format: Article
Language:English
Published: De Gruyter 2019-08-01
Series:Translational Neuroscience
Subjects:
resveratrol
pc12 cells
corticosterone
apoptosis
neurotoxicity
Online Access:https://doi.org/10.1515/tnsci-2019-0038
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spelling doaj-a04a87db807a452692ebd9baee78bc6a2021-09-05T20:51:31ZengDe GruyterTranslational Neuroscience2081-69362019-08-0110123524010.1515/tnsci-2019-0038tnsci-2019-0038Protective effect of resveratrol against corticosterone-induced neurotoxicity in PC12 cellsZhang Ye0He Yun1Deng Ning2Chen Yan3Huang Jiecong4Xie Wei5School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, ChinaDepartment of Orthopedics, Calmett Hospital & The First Hospital of Kunming, Kunming, Yunnan, 650224, ChinaSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, ChinaNormal Human Anatomy and Histological Embryology Department, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan, 650500, ChinaDepartment of Encephalopathy, Guangzhou Conghua Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong, 510900, ChinaSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, ChinaResveratrol(RES) is a natural polyphenol which possesses an anti-depressant effect. However, the mechanisms of its anti-depressant effect remain unclear. The aim of the study is to investigate the potential mechanisms in the neuro-protective efficiency in the corticosterone-induced pheochromacytoma 12 (PC12) cells.https://doi.org/10.1515/tnsci-2019-0038resveratrolpc12 cellscorticosteroneapoptosisneurotoxicity
collection DOAJ
language English
format Article
sources DOAJ
author Zhang Ye
He Yun
Deng Ning
Chen Yan
Huang Jiecong
Xie Wei
spellingShingle Zhang Ye
He Yun
Deng Ning
Chen Yan
Huang Jiecong
Xie Wei
Protective effect of resveratrol against corticosterone-induced neurotoxicity in PC12 cells
Translational Neuroscience
resveratrol
pc12 cells
corticosterone
apoptosis
neurotoxicity
author_facet Zhang Ye
He Yun
Deng Ning
Chen Yan
Huang Jiecong
Xie Wei
author_sort Zhang Ye
title Protective effect of resveratrol against corticosterone-induced neurotoxicity in PC12 cells
title_short Protective effect of resveratrol against corticosterone-induced neurotoxicity in PC12 cells
title_full Protective effect of resveratrol against corticosterone-induced neurotoxicity in PC12 cells
title_fullStr Protective effect of resveratrol against corticosterone-induced neurotoxicity in PC12 cells
title_full_unstemmed Protective effect of resveratrol against corticosterone-induced neurotoxicity in PC12 cells
title_sort protective effect of resveratrol against corticosterone-induced neurotoxicity in pc12 cells
publisher De Gruyter
series Translational Neuroscience
issn 2081-6936
publishDate 2019-08-01
description Resveratrol(RES) is a natural polyphenol which possesses an anti-depressant effect. However, the mechanisms of its anti-depressant effect remain unclear. The aim of the study is to investigate the potential mechanisms in the neuro-protective efficiency in the corticosterone-induced pheochromacytoma 12 (PC12) cells.
topic resveratrol
pc12 cells
corticosterone
apoptosis
neurotoxicity
url https://doi.org/10.1515/tnsci-2019-0038
work_keys_str_mv AT zhangye protectiveeffectofresveratrolagainstcorticosteroneinducedneurotoxicityinpc12cells
AT heyun protectiveeffectofresveratrolagainstcorticosteroneinducedneurotoxicityinpc12cells
AT dengning protectiveeffectofresveratrolagainstcorticosteroneinducedneurotoxicityinpc12cells
AT chenyan protectiveeffectofresveratrolagainstcorticosteroneinducedneurotoxicityinpc12cells
AT huangjiecong protectiveeffectofresveratrolagainstcorticosteroneinducedneurotoxicityinpc12cells
AT xiewei protectiveeffectofresveratrolagainstcorticosteroneinducedneurotoxicityinpc12cells
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