Anticoagulation and monitoring in pediatric extracorporeal membrane oxygenation

Anticoagulation and monitoring in pediatric extracorporeal membrane oxygenation

Anticoagulation during extracorporeal membrane oxygenation (ECMO) is necessary to prevent catastrophic circuit clotting, but hemorrhagic and thrombotic complications continue to contribute to significant morbidity and mortality for patients. Anticoagulation for pediatric patients on ECMO can be part...

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Bibliographic Details
Main Authors: Jamie Weller, Lakshmi Raman, Ali McMichael
Format: Article
Language:English
Published: Wolters Kluwer 2018-12-01
Series:Egyptian Journal of Critical Care Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2090730318300501
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spelling doaj-a054842997e44c43a01e988af355d9dd2020-11-25T01:45:06ZengWolters KluwerEgyptian Journal of Critical Care Medicine2090-73032018-12-01636971Anticoagulation and monitoring in pediatric extracorporeal membrane oxygenationJamie Weller0Lakshmi Raman1Ali McMichael2Correspondence to: Jamie Weller, MD 5323 Harry Hines Blvd, Dallas TX 75390. Tel.: (214) 456 1600.; Pediatric Critical Care, University of Texas Southwestern Medical Center, Dallas, TX, United StatesPediatric Critical Care, University of Texas Southwestern Medical Center, Dallas, TX, United StatesPediatric Critical Care, University of Texas Southwestern Medical Center, Dallas, TX, United StatesAnticoagulation during extracorporeal membrane oxygenation (ECMO) is necessary to prevent catastrophic circuit clotting, but hemorrhagic and thrombotic complications continue to contribute to significant morbidity and mortality for patients. Anticoagulation for pediatric patients on ECMO can be particularly challenging due to their immature hemostasis and the inflammatory response that ensues from the extracorporeal circuit. This review article gives an overview of the various anticoagulants utilized during ECMO and the common tests used to monitor and titrate anticoagulation to minimize complications. Keywords: Anticoagulation, Unfractionated heparin, Bivalirudin, Extracorporeal membrane oxygenationhttp://www.sciencedirect.com/science/article/pii/S2090730318300501
collection DOAJ
language English
format Article
sources DOAJ
author Jamie Weller
Lakshmi Raman
Ali McMichael
spellingShingle Jamie Weller
Lakshmi Raman
Ali McMichael
Anticoagulation and monitoring in pediatric extracorporeal membrane oxygenation
Egyptian Journal of Critical Care Medicine
author_facet Jamie Weller
Lakshmi Raman
Ali McMichael
author_sort Jamie Weller
title Anticoagulation and monitoring in pediatric extracorporeal membrane oxygenation
title_short Anticoagulation and monitoring in pediatric extracorporeal membrane oxygenation
title_full Anticoagulation and monitoring in pediatric extracorporeal membrane oxygenation
title_fullStr Anticoagulation and monitoring in pediatric extracorporeal membrane oxygenation
title_full_unstemmed Anticoagulation and monitoring in pediatric extracorporeal membrane oxygenation
title_sort anticoagulation and monitoring in pediatric extracorporeal membrane oxygenation
publisher Wolters Kluwer
series Egyptian Journal of Critical Care Medicine
issn 2090-7303
publishDate 2018-12-01
description Anticoagulation during extracorporeal membrane oxygenation (ECMO) is necessary to prevent catastrophic circuit clotting, but hemorrhagic and thrombotic complications continue to contribute to significant morbidity and mortality for patients. Anticoagulation for pediatric patients on ECMO can be particularly challenging due to their immature hemostasis and the inflammatory response that ensues from the extracorporeal circuit. This review article gives an overview of the various anticoagulants utilized during ECMO and the common tests used to monitor and titrate anticoagulation to minimize complications. Keywords: Anticoagulation, Unfractionated heparin, Bivalirudin, Extracorporeal membrane oxygenation
url http://www.sciencedirect.com/science/article/pii/S2090730318300501
work_keys_str_mv AT jamieweller anticoagulationandmonitoringinpediatricextracorporealmembraneoxygenation
AT lakshmiraman anticoagulationandmonitoringinpediatricextracorporealmembraneoxygenation
AT alimcmichael anticoagulationandmonitoringinpediatricextracorporealmembraneoxygenation
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