Bioactive flavonoids in medicinal plants: Structure, activity and biological fate
Flavonoids, a class of polyphenol secondary metabolites, are presented broadly in plants and diets. They are believed to have various bioactive effects including anti-viral, anti-inflammatory, cardioprotective, anti-diabetic, anti-cancer, anti-aging, etc. Their basic structures consist of C6C3C6 r...
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doaj-a056882cb69a4be281516f22edd9d89b2020-11-25T00:37:52ZengElsevierAsian Journal of Pharmaceutical Sciences1818-08762018-01-01131122310.1016/j.ajps.2017.08.004Bioactive flavonoids in medicinal plants: Structure, activity and biological fateTian-yang WangQing LiKai-shun BiFlavonoids, a class of polyphenol secondary metabolites, are presented broadly in plants and diets. They are believed to have various bioactive effects including anti-viral, anti-inflammatory, cardioprotective, anti-diabetic, anti-cancer, anti-aging, etc. Their basic structures consist of C6C3C6 rings with different substitution patterns to produce a series of subclass compounds, and correlations between chemical structures and bioactivities have been studied before. Given their poor bioavailability, however, information about associations between structure and biological fate is limited and urgently needed. This review therefore attempts to bring some order into relationships between structure, activity as well as pharmacokinetics of bioactive flavonoids.http://www.sciencedirect.com/science/article/pii/S1818087617301940FlavonoidActivityStructurePharmacokineticsBioavailability |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Tian-yang Wang Qing Li Kai-shun Bi |
spellingShingle |
Tian-yang Wang Qing Li Kai-shun Bi Bioactive flavonoids in medicinal plants: Structure, activity and biological fate Asian Journal of Pharmaceutical Sciences Flavonoid Activity Structure Pharmacokinetics Bioavailability |
author_facet |
Tian-yang Wang Qing Li Kai-shun Bi |
author_sort |
Tian-yang Wang |
title |
Bioactive flavonoids in medicinal plants: Structure, activity and biological fate |
title_short |
Bioactive flavonoids in medicinal plants: Structure, activity and biological fate |
title_full |
Bioactive flavonoids in medicinal plants: Structure, activity and biological fate |
title_fullStr |
Bioactive flavonoids in medicinal plants: Structure, activity and biological fate |
title_full_unstemmed |
Bioactive flavonoids in medicinal plants: Structure, activity and biological fate |
title_sort |
bioactive flavonoids in medicinal plants: structure, activity and biological fate |
publisher |
Elsevier |
series |
Asian Journal of Pharmaceutical Sciences |
issn |
1818-0876 |
publishDate |
2018-01-01 |
description |
Flavonoids, a class of polyphenol secondary metabolites, are presented broadly in plants and diets. They are believed to have various bioactive effects including anti-viral, anti-inflammatory, cardioprotective, anti-diabetic, anti-cancer, anti-aging, etc. Their basic structures consist of C6C3C6 rings with different substitution patterns to produce a series of subclass compounds, and correlations between chemical structures and bioactivities have been studied before. Given their poor bioavailability, however, information about associations between structure and biological fate is limited and urgently needed. This review therefore attempts to bring some order into relationships between structure, activity as well as pharmacokinetics of bioactive flavonoids. |
topic |
Flavonoid Activity Structure Pharmacokinetics Bioavailability |
url |
http://www.sciencedirect.com/science/article/pii/S1818087617301940 |
work_keys_str_mv |
AT tianyangwang bioactiveflavonoidsinmedicinalplantsstructureactivityandbiologicalfate AT qingli bioactiveflavonoidsinmedicinalplantsstructureactivityandbiologicalfate AT kaishunbi bioactiveflavonoidsinmedicinalplantsstructureactivityandbiologicalfate |
_version_ |
1725299336312520704 |