Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer’s disease

Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer’s disease

Abstract Background Chitinase 3-like 1 (CHI3L1), chitinase 3-like 2 (CHI3L2), and neuronal pentraxin II (NPTX2) are inflammatory biomarkers of Alzheimer’s disease (AD). Although studies have demonstrated that cerebrospinal fluid levels of these proteins are changed in AD, no studies have undertaken...

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Bibliographic Details
Main Authors: Marta Moreno-Rodriguez, Sylvia E. Perez, Muhammad Nadeem, Michael Malek-Ahmadi, Elliott J. Mufson
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Neuroinflammation
Subjects:
Alzheimer’s disease
Astrocytes
Chitinase
Cognitive impairment
Frontal cortex
Gray matter
Online Access:http://link.springer.com/article/10.1186/s12974-020-1723-x

Internet

http://link.springer.com/article/10.1186/s12974-020-1723-x

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