Post kala-azar dermal leishmaniasis: Clinical features and differential diagnosis
Post kala-azar dermal leishmaniasis (PKDL) is a mucocutaneous disease usually seen in apparently cured, inadequately treated or untreated cases of visceral leishmaniasis and is endemic to many parts of India, Nepal, Bangladesh, and eastern Africa (Sudan, Ethiopia, Kenya). The disease usually manifes...
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doaj-a05d5274edb84b898f2bb09db5222b592021-02-19T09:26:30ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112021-01-01661243310.4103/ijd.IJD_602_20Post kala-azar dermal leishmaniasis: Clinical features and differential diagnosisPiyush KumarMitali ChatterjeeNilay Kanti DasPost kala-azar dermal leishmaniasis (PKDL) is a mucocutaneous disease usually seen in apparently cured, inadequately treated or untreated cases of visceral leishmaniasis and is endemic to many parts of India, Nepal, Bangladesh, and eastern Africa (Sudan, Ethiopia, Kenya). The disease usually manifests as a variable combination of hypopigmented patches, erythematous succulent papulo-plaques, and nodular lesions on the face and upper body and sometimes extending on the extremities, genitalia, and tongue. Atypical morphology and presentations are not uncommon, especially in endemic areas, which include photosensitivity, verrucous, hypertrophic, xanthomatous, and ulcerative lesions. Recognition of spectrum of mucocutaneous changes helps physicians in early initiation of treatment and in reducing disease transmission in the community. The differential diagnosis depends on the pattern of manifestations, but lepromatous leprosy is the closest mimicker. Since PKDL does not cause significant morbidity, at least initially, but the affected patients continue to act as a reservoir of the disease, active case detection is required to identify cases early to control the disease transmission in the community.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2021;volume=66;issue=1;spage=24;epage=33;aulast=Kumaractive surveillanceindialeishmania donovanipara kala-azar dermal leishmaniasispost kala-azar dermal leishmaniasissudanvisceral leishmaniasis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Piyush Kumar Mitali Chatterjee Nilay Kanti Das |
spellingShingle |
Piyush Kumar Mitali Chatterjee Nilay Kanti Das Post kala-azar dermal leishmaniasis: Clinical features and differential diagnosis Indian Journal of Dermatology active surveillance india leishmania donovani para kala-azar dermal leishmaniasis post kala-azar dermal leishmaniasis sudan visceral leishmaniasis |
author_facet |
Piyush Kumar Mitali Chatterjee Nilay Kanti Das |
author_sort |
Piyush Kumar |
title |
Post kala-azar dermal leishmaniasis: Clinical features and differential diagnosis |
title_short |
Post kala-azar dermal leishmaniasis: Clinical features and differential diagnosis |
title_full |
Post kala-azar dermal leishmaniasis: Clinical features and differential diagnosis |
title_fullStr |
Post kala-azar dermal leishmaniasis: Clinical features and differential diagnosis |
title_full_unstemmed |
Post kala-azar dermal leishmaniasis: Clinical features and differential diagnosis |
title_sort |
post kala-azar dermal leishmaniasis: clinical features and differential diagnosis |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Dermatology |
issn |
0019-5154 1998-3611 |
publishDate |
2021-01-01 |
description |
Post kala-azar dermal leishmaniasis (PKDL) is a mucocutaneous disease usually seen in apparently cured, inadequately treated or untreated cases of visceral leishmaniasis and is endemic to many parts of India, Nepal, Bangladesh, and eastern Africa (Sudan, Ethiopia, Kenya). The disease usually manifests as a variable combination of hypopigmented patches, erythematous succulent papulo-plaques, and nodular lesions on the face and upper body and sometimes extending on the extremities, genitalia, and tongue. Atypical morphology and presentations are not uncommon, especially in endemic areas, which include photosensitivity, verrucous, hypertrophic, xanthomatous, and ulcerative lesions. Recognition of spectrum of mucocutaneous changes helps physicians in early initiation of treatment and in reducing disease transmission in the community. The differential diagnosis depends on the pattern of manifestations, but lepromatous leprosy is the closest mimicker. Since PKDL does not cause significant morbidity, at least initially, but the affected patients continue to act as a reservoir of the disease, active case detection is required to identify cases early to control the disease transmission in the community. |
topic |
active surveillance india leishmania donovani para kala-azar dermal leishmaniasis post kala-azar dermal leishmaniasis sudan visceral leishmaniasis |
url |
http://www.e-ijd.org/article.asp?issn=0019-5154;year=2021;volume=66;issue=1;spage=24;epage=33;aulast=Kumar |
work_keys_str_mv |
AT piyushkumar postkalaazardermalleishmaniasisclinicalfeaturesanddifferentialdiagnosis AT mitalichatterjee postkalaazardermalleishmaniasisclinicalfeaturesanddifferentialdiagnosis AT nilaykantidas postkalaazardermalleishmaniasisclinicalfeaturesanddifferentialdiagnosis |
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