Focused ultrasound guided relocation of kidney stones
Purpose: Complete removal of all fragments is the goal of any intervention for urinary stones. This is more important in lower pole stones where gravity and spatial orientation of lower pole infundibulum may hinder spontaneous passage of fragments. Various adjuvant therapies (inversion, diuresis, pe...
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doaj-a07e3f476cab4120b1cfe5e3156f8ea32020-11-24T23:25:23ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242015-01-01311283210.4103/0970-1591.139577Focused ultrasound guided relocation of kidney stonesNitin AbrolNitin S KekrePurpose: Complete removal of all fragments is the goal of any intervention for urinary stones. This is more important in lower pole stones where gravity and spatial orientation of lower pole infundibulum may hinder spontaneous passage of fragments. Various adjuvant therapies (inversion, diuresis, percussion, oral citrate, etc.) are described to enhance stone-free rate but are not widely accepted. Focused ultrasound-guided relocation of fragments is a recently described technique aimed at improving results of intervention for stone disease. Purpose of this review is to discuss development of this technology and its potential clinical applications. Materials and Methods: Pubmed search was made using key words "Focused ultrasound" and "kidney stone." All English language articles were reviewed by title. Relevant studies describing development and application of focused ultrasound in renal stones were selected for review. Results: Focused ultrasound has proven its efficacy in successfully relocating up to 8 mm stone fragments in vitro and in pigs. Relocation is independent of stone composition. The latest model allows imaging and therapy with a single handheld probe facilitating its use by single operator. The acoustic energy delivered by the new prototype is even less than that used for extracorporeal shock wave lithotripsy. Therapeutic exposure has not caused thermal injury in pig kidneys. Conclusion: Focused ultrasound-guided relocation of stones is feasible. Though it is safe in application in pigs, technology is awaiting approval for clinical testing in human beings. This technology has many potential clinical applications in the management of stone disease.http://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=1;spage=28;epage=32;aulast=AbrolFocused ultrasoundrelocationrenal calculistone-free rate |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nitin Abrol Nitin S Kekre |
spellingShingle |
Nitin Abrol Nitin S Kekre Focused ultrasound guided relocation of kidney stones Indian Journal of Urology Focused ultrasound relocation renal calculi stone-free rate |
author_facet |
Nitin Abrol Nitin S Kekre |
author_sort |
Nitin Abrol |
title |
Focused ultrasound guided relocation of kidney stones |
title_short |
Focused ultrasound guided relocation of kidney stones |
title_full |
Focused ultrasound guided relocation of kidney stones |
title_fullStr |
Focused ultrasound guided relocation of kidney stones |
title_full_unstemmed |
Focused ultrasound guided relocation of kidney stones |
title_sort |
focused ultrasound guided relocation of kidney stones |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Urology |
issn |
0970-1591 1998-3824 |
publishDate |
2015-01-01 |
description |
Purpose: Complete removal of all fragments is the goal of any intervention for urinary stones. This is more important in lower pole stones where gravity and spatial orientation of lower pole infundibulum may hinder spontaneous passage of fragments. Various adjuvant therapies (inversion, diuresis, percussion, oral citrate, etc.) are described to enhance stone-free rate but are not widely accepted. Focused ultrasound-guided relocation of fragments is a recently described technique aimed at improving results of intervention for stone disease. Purpose of this review is to discuss development of this technology and its potential clinical applications.
Materials and Methods: Pubmed search was made using key words "Focused ultrasound" and "kidney stone." All English language articles were reviewed by title. Relevant studies describing development and application of focused ultrasound in renal stones were selected for review.
Results: Focused ultrasound has proven its efficacy in successfully relocating up to 8 mm stone fragments in vitro and in pigs. Relocation is independent of stone composition. The latest model allows imaging and therapy with a single handheld probe facilitating its use by single operator. The acoustic energy delivered by the new prototype is even less than that used for extracorporeal shock wave lithotripsy. Therapeutic exposure has not caused thermal injury in pig kidneys.
Conclusion: Focused ultrasound-guided relocation of stones is feasible. Though it is safe in application in pigs, technology is awaiting approval for clinical testing in human beings. This technology has many potential clinical applications in the management of stone disease. |
topic |
Focused ultrasound relocation renal calculi stone-free rate |
url |
http://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=1;spage=28;epage=32;aulast=Abrol |
work_keys_str_mv |
AT nitinabrol focusedultrasoundguidedrelocationofkidneystones AT nitinskekre focusedultrasoundguidedrelocationofkidneystones |
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