Genetic polymorphisms and epigenetic regulation of survivin encoding gene, BIRC5, in multiple sclerosis patients

Genetic polymorphisms and epigenetic regulation of survivin encoding gene, BIRC5, in multiple sclerosis patients

Abstract Background The persistent the inflammatory condition in multiple sclerosis (MS) may due to the aberrant regulation of the elimination of the pathogenic autoreactive lymphocytes through apoptosis. Survivin, encoded by the BIRC5 gene, has been indicated to be involved in the regulation of apo...

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Bibliographic Details
Main Authors: Dariush Rahban, Forogh Mohammadi, Mehdi Alidadi, Taha Ghantabpour, Pedram Abbasi Ghasem Kheyli, Majid Ahmadi
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Immunology
Subjects:
Multiple sclerosis
BIRC5 gene
Survivin
Apoptosis
microRNA
Online Access:http://link.springer.com/article/10.1186/s12865-019-0312-1

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