The high-risk HPV E6 target scribble (hScrib) is required for HPV E6 expression in cervical tumour-derived cell lines
The ability of high-risk HPV E6 oncoproteins to target cellular proteins which harbor PDZ domains is believed to play an important role in the virus life cycle and to influence the ability of these viruses to bring about malignant transformation. Whilst many of these PDZ proteins are potential tumou...
Main Authors: | Christian Kranjec, Vjekoslav Tomaić, Paola Massimi, Lietta Nicolaides, John Doorbar, Lawrence Banks |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-12-01
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Series: | Papillomavirus Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405852115300136 |
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