Defining the proteolytic landscape during enterovirus infection.

Viruses cleave cellular proteins to remodel the host proteome. The study of these cleavages has revealed mechanisms of immune evasion, resource exploitation, and pathogenesis. However, the full extent of virus-induced proteolysis in infected cells is unknown, mainly because until recently the techno...

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Main Authors: Mohsan Saeed, Sebastian Kapell, Nicholas T Hertz, Xianfang Wu, Kierstin Bell, Alison W Ashbrook, Milica Tesic Mark, Henry A Zebroski, Maxwell L Neal, Malin Flodström-Tullberg, Margaret R MacDonald, John D Aitchison, Henrik Molina, Charles M Rice
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008927