Farnesol stimulates laccase production in Trametes versicolor

Farnesol stimulates laccase production in Trametes versicolor

Farnesol, a quorum‐sensing molecule, was used successfully to improve laccase production in submerged cultures of Trametes versicolor. At the optimal farnesol concentration of 60 μM added at the beginning of the culture, the extracellular laccase activity reached 629.3 U L−1 after 6 days of cultivat...

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Bibliographic Details
Main Authors: Jianhua Hu, Feng Wang, Anzhou Ma, Guoqiang Zhuang, Ying Liu, Jingsong Lu, Chen Guo, Chunzhao Liu
Format: Article
Language:English
Published: Wiley-VCH 2016-05-01
Series:Engineering in Life Sciences
Subjects:
Farnesol
Hyperbranch
Laccase
Quorum sensing
Trametes versicolor
Online Access:https://doi.org/10.1002/elsc.201500082
Description
Summary:Farnesol, a quorum‐sensing molecule, was used successfully to improve laccase production in submerged cultures of Trametes versicolor. At the optimal farnesol concentration of 60 μM added at the beginning of the culture, the extracellular laccase activity reached 629.3 U L−1 after 6 days of cultivation, which represented a 1.92‐fold increase relative to the control without farnesol treatment. The addition of farnesol resulted in an increase in the accumulation of H2O2 and an increased expression of the laccase (lac) gene and the RhoA gene. The RhoA gene correlated with hyperbranched mycelia, which facilitated the secretion of the intracellular laccase. This study provides a basis for understanding the induction mechanism of farnesol for enhancing laccase production.
ISSN:1618-0240
1618-2863

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