Impact of tuberculosis treatment and antiretroviral therapy on serial RD-1-specific quantitative T-cell readouts (QuantiFERON-TB Gold In-Tube), and relationship to treatment-related outcomes and bacterial burden

Impact of tuberculosis treatment and antiretroviral therapy on serial RD-1-specific quantitative T-cell readouts (QuantiFERON-TB Gold In-Tube), and relationship to treatment-related outcomes and bacterial burden

Background: The impact of anti-tuberculosis treatment with and without antiretroviral therapy (ART) on standardized interferon gamma release assay (IGRA) readouts has been studied inadequately in high-burden countries. Methods: The QuantiFERON-TB Gold In-Tube (QFT-GIT) test was used to evaluate inte...

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Bibliographic Details
Main Authors: Thuli Mthiyane, Roxana Rustomjee, Alex Pym, Cathy Connolly, Philip Onyebujoh, Grant Theron, Keertan Dheda
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:International Journal of Infectious Diseases
Subjects:
Tuberculosis
HIV
Antiretrovirals
Interferon gamma release assay
QuantiFERON-TB Gold In-Tube
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971215001137

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