Deciphering MET‐dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics

Deciphering MET‐dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics

Increasing evidence suggests that interference with growth factor receptor tyrosine kinase (RTK) signaling can affect DNA damage response (DDR) networks, with a consequent impact on cellular responses to DNA‐damaging agents widely used in cancer treatment. In that respect, the MET RTK is deregulated...

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Bibliographic Details
Main Authors: Ariel Bensimon, Jonas P. Koch, Paola Francica, Selina M. Roth, Rahel Riedo, Astrid A. Glück, Eleonora Orlando, Andree Blaukat, Daniel M. Aebersold, Yitzhak Zimmer, Ruedi Aebersold, Michaela Medová
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Molecular Oncology
Subjects:
ATM
DNA damage response
ionizing radiation
mass spectrometry
MET
receptor tyrosine kinase
Online Access:https://doi.org/10.1002/1878-0261.12696

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