Notch1 Activation Up-Regulates Pancreatic and Duodenal Homeobox-1
Transcription factor pancreatic and duodenal homeobox-1 (PDX-1) plays an essential role in pancreatic development, β-cell differentiation, maintenance of normal β-cell function and tumorigenesis. PDX-1 expression is tightly controlled through a variety of mechanisms under different cellular contexts...
Main Authors: | Min Li, F. Charles Brunicardi, William E. Fisher, David Dawson, Neil Senzer, James Wu, John Nemunaitis, Shi-He Liu, Guisheng Zhou, Juehua Yu |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-07-01
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Series: | Genes |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4425/4/3/358 |
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