A Case of Pregnancy Combined with Congenital Osteogenesis Imperfecta

• Main Authors: Yun-Hui Tang, Xiao-Ying Yao
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2017-01-01
• Series: Reproductive and Developmental Medicine
• Subjects: Abortion; Congenital Osteogenesis Imperfecta; Pregnancy
• Online Access: http://www.repdevmed.org/article.asp?issn=2096-2924;year=2017;volume=1;issue=3;spage=184;epage=186;aulast=Tang

Congenital osteogenesis imperfecta is a rare autosomal dominant genetic disease. Pregnant women with the disease pose a treatment challenge to doctors who cannot predict the pregnancy outcome and recommend an appropriate abortive approach. We present the case report of a 26-year-old female who showed typical symptom of congenital osteogenesis imperfecta. Considering the heredity of the disease, the patient and her family decided to prematurely terminate the gestation. The patient presented with a treatment dilemma was difficult to identify a route of uterine entry because it was impossible to prop the patient in a lithotomy position. After consulting with the patient, the pregnancy was terminated by cesarean delivery. The surgery was successful; in our opinion, however, the cesarean delivery was not the best abortive approach to use in this case because of the severity of the procedure and the complications that could have arisen from it. Further studies are needed to identify a better abortive approach for similar cases.