Hypereosinophilic syndrome mimicking acute coronary syndrome

• Main Authors: Pulkit Chhabra, Deepak Jain, H K Aggarwal, Sudhir Mor, Promil Jain
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2017-01-01
• Series: Heart India
• Subjects: Acute coronary syndrome; heart failure; hypereosinophilic syndrome; myocarditis
• Online Access: http://www.heartindia.net/article.asp?issn=2321-449x;year=2017;volume=5;issue=2;spage=77;epage=81;aulast=Chhabra

Hypereosinophilic syndrome (HES) is a heterogeneous group of disorders with peripheral blood hypereosinophilia and eosinophil-mediated organ involvement. It may be primary, secondary, or idiopathic. In very rare cases, HES can be familial occurring as an autosomal dominant disorder. Cardiac involvement usually presents as heart failure, intracardiac thrombus, arrhythmias, and rarely as acute coronary syndrome (ACS) and is a major cause of morbidity and mortality. Cardiac magnetic resonance imaging has emerged as a diagnostic modality in diagnosis of eosinophilic endomyocardial disease. We report a case of a young male with familial HES presenting as ACS and discuss diagnostic and therapeutic clinical management.