Investigations into the Sarcomeric Protein and Ca2+-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus)

Investigations into the Sarcomeric Protein and Ca2+-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus)

Hypertrophic cardiomyopathy (HCM) is the most common single gene inherited cardiomyopathy. In cats (Felix catus) HCM is even more prevalent and affects 16% of the outbred population and up to 26% in pedigree breeds such as Maine Coon and Ragdoll. Homozygous MYBPC3 mutations have been identified in t...

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Bibliographic Details
Main Authors: Andrew E. Messer, Jasmine Chan, Alex Daley, O'Neal Copeland, Steven B. Marston, David J. Connolly
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Physiology
Subjects:
Felix catus
Ragdoll cat
hypertrophic cardiomyopathy
cardiac muscle
Ca2+ regulation
troponin
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00348/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.00348/full

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