Receptor Heterodimerization and Co-Receptor Engagement in TLR2 Activation Induced by MIC1 and MIC4 from <em>Toxoplasma gondii</em>
The microneme organelles of <i>Toxoplasma gondii</i> tachyzoites release protein complexes (MICs), including one composed of the transmembrane protein MIC6 plus MIC1 and MIC4. In this complex, carbohydrate recognition domains of MIC1 and MIC4 are exposed and interact with terminal sialic...
Main Authors: | Flávia Costa Mendonça-Natividade, Carla Duque Lopes, Rafael Ricci-Azevedo, Aline Sardinha-Silva, Camila Figueiredo Pinzan, Ana Claudia Paiva Alegre-Maller, Lilian L. Nohara, Alan B. Carneiro, Ademilson Panunto-Castelo, Igor C. Almeida, Maria Cristina Roque-Barreira |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-10-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/20/5001 |
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