The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study)
Background: Among atopic diseases, atopic dermatitis is the most common allergic disease in children and influences both infantile and parental quality of life. Objective: The present study investigated the sex-specific relationship between the fetal/placental weight ratio and The incidence of atopi...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-06-01
|
Series: | International Journal of Women's Dermatology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352647520300216 |
id |
doaj-a17b11c0bd264563a15bab3ef8731d70 |
---|---|
record_format |
Article |
spelling |
doaj-a17b11c0bd264563a15bab3ef8731d702020-11-25T03:54:32ZengElsevierInternational Journal of Women's Dermatology2352-64752020-06-0163176181The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study)Masako Matsumoto, MD0Kenji J. Tsuchiya, MD PhD1Chizuko Yaguchi, MD PhD2Yoshimasa Horikoshi, MD3Naomi Furuta-Isomura, MD PhD4Tomoaki Oda, MD PhD5Yukiko Kohmura-Kobayashi, MD PhD6Naoaki Tamura, MD PhD7Toshiyuki Uchida, MD PhD8Hiroaki Itoh, MD DMedSci9Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, JapanResearch Center for Child Mental Development, Hamamatsu University School of Medicine, Hamamatsu, JapanDepartment of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, JapanDepartment of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, JapanDepartment of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, JapanDepartment of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, JapanDepartment of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, JapanDepartment of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, JapanDepartment of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, JapanDepartment of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, Japan; Corresponding author.Background: Among atopic diseases, atopic dermatitis is the most common allergic disease in children and influences both infantile and parental quality of life. Objective: The present study investigated the sex-specific relationship between the fetal/placental weight ratio and The incidence of atopic dermatitis in infants during the first 14 months of life. Methods: Study participants were 922 infants (462 female and 460 male) from singleton pregnancies enrolled in the Hamamatsu Birth Cohort for Mothers and Children (HBC Study) after the exclusion of 298 with missing data on atopic dermatitis. The enrollment of infants with atopic dermatitis was based on a positive response from parents regarding whether a physician had ever diagnosed their child with atopic dermatitis by 14 months of age. The two-sample Wilcoxon rank-sum test or χ2 test was adopted for descriptive analyses where appropriate. Unadjusted odds ratios and 95% confidence intervals for the infantile incidence of atopic dermatitis were compared using logistic regression analyses. Results: Maternal and perinatal factors did not correlate with the incidence of infantile atopic dermatitis. Fetal/placental weight ratio, but not birth or placental weight, correlated with the incidence of atopic dermatitis in female, but not male, infants. A correlation was still observed after adjustments for maternal allergies, gestational age at birth, maternal smoking during pregnancy, and household income at birth (odds ratio: 1.57; 95% confidence interval, 1.05–2.33). Conclusion: We speculated that the intrauterine fetal environment, represented by a relatively small placenta, programs a predisposition in only female infants to atopic dermatitis during the first 14 months of life.http://www.sciencedirect.com/science/article/pii/S2352647520300216AllergyAtopic dermatitisFemale infantsFetal/placental weight ratioPlacentaPregnancy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Masako Matsumoto, MD Kenji J. Tsuchiya, MD PhD Chizuko Yaguchi, MD PhD Yoshimasa Horikoshi, MD Naomi Furuta-Isomura, MD PhD Tomoaki Oda, MD PhD Yukiko Kohmura-Kobayashi, MD PhD Naoaki Tamura, MD PhD Toshiyuki Uchida, MD PhD Hiroaki Itoh, MD DMedSci |
spellingShingle |
Masako Matsumoto, MD Kenji J. Tsuchiya, MD PhD Chizuko Yaguchi, MD PhD Yoshimasa Horikoshi, MD Naomi Furuta-Isomura, MD PhD Tomoaki Oda, MD PhD Yukiko Kohmura-Kobayashi, MD PhD Naoaki Tamura, MD PhD Toshiyuki Uchida, MD PhD Hiroaki Itoh, MD DMedSci The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study) International Journal of Women's Dermatology Allergy Atopic dermatitis Female infants Fetal/placental weight ratio Placenta Pregnancy |
author_facet |
Masako Matsumoto, MD Kenji J. Tsuchiya, MD PhD Chizuko Yaguchi, MD PhD Yoshimasa Horikoshi, MD Naomi Furuta-Isomura, MD PhD Tomoaki Oda, MD PhD Yukiko Kohmura-Kobayashi, MD PhD Naoaki Tamura, MD PhD Toshiyuki Uchida, MD PhD Hiroaki Itoh, MD DMedSci |
author_sort |
Masako Matsumoto, MD |
title |
The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study) |
title_short |
The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study) |
title_full |
The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study) |
title_fullStr |
The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study) |
title_full_unstemmed |
The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study) |
title_sort |
fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: the hamamatsu birth cohort for mothers and children (hbc study) |
publisher |
Elsevier |
series |
International Journal of Women's Dermatology |
issn |
2352-6475 |
publishDate |
2020-06-01 |
description |
Background: Among atopic diseases, atopic dermatitis is the most common allergic disease in children and influences both infantile and parental quality of life. Objective: The present study investigated the sex-specific relationship between the fetal/placental weight ratio and The incidence of atopic dermatitis in infants during the first 14 months of life. Methods: Study participants were 922 infants (462 female and 460 male) from singleton pregnancies enrolled in the Hamamatsu Birth Cohort for Mothers and Children (HBC Study) after the exclusion of 298 with missing data on atopic dermatitis. The enrollment of infants with atopic dermatitis was based on a positive response from parents regarding whether a physician had ever diagnosed their child with atopic dermatitis by 14 months of age. The two-sample Wilcoxon rank-sum test or χ2 test was adopted for descriptive analyses where appropriate. Unadjusted odds ratios and 95% confidence intervals for the infantile incidence of atopic dermatitis were compared using logistic regression analyses. Results: Maternal and perinatal factors did not correlate with the incidence of infantile atopic dermatitis. Fetal/placental weight ratio, but not birth or placental weight, correlated with the incidence of atopic dermatitis in female, but not male, infants. A correlation was still observed after adjustments for maternal allergies, gestational age at birth, maternal smoking during pregnancy, and household income at birth (odds ratio: 1.57; 95% confidence interval, 1.05–2.33). Conclusion: We speculated that the intrauterine fetal environment, represented by a relatively small placenta, programs a predisposition in only female infants to atopic dermatitis during the first 14 months of life. |
topic |
Allergy Atopic dermatitis Female infants Fetal/placental weight ratio Placenta Pregnancy |
url |
http://www.sciencedirect.com/science/article/pii/S2352647520300216 |
work_keys_str_mv |
AT masakomatsumotomd thefetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT kenjijtsuchiyamdphd thefetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT chizukoyaguchimdphd thefetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT yoshimasahorikoshimd thefetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT naomifurutaisomuramdphd thefetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT tomoakiodamdphd thefetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT yukikokohmurakobayashimdphd thefetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT naoakitamuramdphd thefetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT toshiyukiuchidamdphd thefetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT hiroakiitohmddmedsci thefetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT masakomatsumotomd fetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT kenjijtsuchiyamdphd fetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT chizukoyaguchimdphd fetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT yoshimasahorikoshimd fetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT naomifurutaisomuramdphd fetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT tomoakiodamdphd fetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT yukikokohmurakobayashimdphd fetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT naoakitamuramdphd fetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT toshiyukiuchidamdphd fetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy AT hiroakiitohmddmedsci fetalplacentalweightratioisassociatedwiththeincidenceofatopicdermatitisinfemaleinfantsduringthefirst14monthsthehamamatsubirthcohortformothersandchildrenhbcstudy |
_version_ |
1724473182461624320 |