Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice
Even though the idea that amyloid β peptide accumulation is the primary event in the pathogenesis of Alzheimer's disease has become the leading hypothesis, the causal link between aberrant amyloid precursor protein processing and tau alterations in this type of dementia remains controversial. W...
Main Authors: | Elena M. Ribé, Mar Pérez, Berta Puig, Ignasi Gich, Filip Lim, Mar Cuadrado, Teresa Sesma, Silvia Catena, Belén Sánchez, María Nieto, Pilar Gómez-Ramos, M.Asunción Morán, Felipe Cabodevilla, Lluis Samaranch, Lourdes Ortiz, Alberto Pérez, Isidro Ferrer, Jesús Avila, Teresa Gómez-Isla |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2005-12-01
|
Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S096999610500152X |
Similar Items
-
A ß-Secretase Modulator Decreases Tau Pathology and Preserves Short-Term Memory in a Mouse Model of Neurofibrillary Degeneration
by: Marie Tautou, et al.
Published: (2021-06-01) -
Selective spatiotemporal patterns of glial activation and neuron loss in the sensory thalamocortical pathways of neuronal ceroid lipofuscinosis 8 mice
by: Mervi Kuronen, et al.
Published: (2012-09-01) -
The role of extracellular Tau in the spreading of neurofibrillary pathology
by: Miguel eMedina, et al.
Published: (2014-04-01) -
A HISTORY OF THE STEREOLOGY IN CHINA
by: Li Wang, et al.
Published: (2018-04-01) -
25 YEARS OF THE POLISH SOCIETY FOR STEREOLOGY
by: Leszek Wojnar
Published: (2013-11-01)