The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study
The mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. In this study the effect of lead acetate on the hippocampal constitutive nitric oxide production was studied. The variation in the nitric oxide production may contribute to physiological l...
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Tehran University of Medical Sciences
2001-03-01
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doaj-a199cd283cd04e65909c52bdd867963c2020-11-25T03:30:17ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942001-03-01391The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study "Ghane T0 Kebriaezadeh A1 Azizi E2 Dehpour AR3 Ostad SN "4 The mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. In this study the effect of lead acetate on the hippocampal constitutive nitric oxide production was studied. The variation in the nitric oxide production may contribute to physiological lead neurotoxicity in vivo. Different concentrations of lead acetate (10-9 to 10-6 M), wre added to cultures of hippocampal pyramidal cell obtained from one-day newborn rats. Sodium acetate was used as control. In this range of stuy viability of cells did not alter when it was compared to control (Phttps://acta.tums.ac.ir/index.php/acta/article/view/2340Pyramidal cellChronic toxicityRat hippocampal cells |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
"Ghane T Kebriaezadeh A Azizi E Dehpour AR Ostad SN " |
spellingShingle |
"Ghane T Kebriaezadeh A Azizi E Dehpour AR Ostad SN " The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study Acta Medica Iranica Pyramidal cell Chronic toxicity Rat hippocampal cells |
author_facet |
"Ghane T Kebriaezadeh A Azizi E Dehpour AR Ostad SN " |
author_sort |
"Ghane T |
title |
The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study |
title_short |
The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study |
title_full |
The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study |
title_fullStr |
The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study |
title_full_unstemmed |
The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study |
title_sort |
effect of lead acetate on the nitric oxide system in the rat hippocampal cells: an in-vitro study |
publisher |
Tehran University of Medical Sciences |
series |
Acta Medica Iranica |
issn |
0044-6025 1735-9694 |
publishDate |
2001-03-01 |
description |
The mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. In this study the effect of lead acetate on the hippocampal constitutive nitric oxide production was studied. The variation in the nitric oxide production may contribute to physiological lead neurotoxicity in vivo. Different concentrations of lead acetate (10-9 to 10-6 M), wre added to cultures of hippocampal pyramidal cell obtained from one-day newborn rats. Sodium acetate was used as control. In this range of stuy viability of cells did not alter when it was compared to control (P |
topic |
Pyramidal cell Chronic toxicity Rat hippocampal cells |
url |
https://acta.tums.ac.ir/index.php/acta/article/view/2340 |
work_keys_str_mv |
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