The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study

The mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. In this study the effect of lead acetate on the hippocampal constitutive nitric oxide production was studied. The variation in the nitric oxide production may contribute to physiological l...

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Main Authors: "Ghane T, Kebriaezadeh A, Azizi E, Dehpour AR, Ostad SN "
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2001-03-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/2340
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spelling doaj-a199cd283cd04e65909c52bdd867963c2020-11-25T03:30:17ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942001-03-01391The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study "Ghane T0 Kebriaezadeh A1 Azizi E2 Dehpour AR3 Ostad SN "4 The mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. In this study the effect of lead acetate on the hippocampal constitutive nitric oxide production was studied. The variation in the nitric oxide production may contribute to physiological lead neurotoxicity in vivo. Different concentrations of lead acetate (10-9 to 10-6 M), wre added to cultures of hippocampal pyramidal cell obtained from one-day newborn rats. Sodium acetate was used as control. In this range of stuy viability of cells did not alter when it was compared to control (Phttps://acta.tums.ac.ir/index.php/acta/article/view/2340Pyramidal cellChronic toxicityRat hippocampal cells
collection DOAJ
language English
format Article
sources DOAJ
author "Ghane T
Kebriaezadeh A
Azizi E
Dehpour AR
Ostad SN "
spellingShingle "Ghane T
Kebriaezadeh A
Azizi E
Dehpour AR
Ostad SN "
The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study
Acta Medica Iranica
Pyramidal cell
Chronic toxicity
Rat hippocampal cells
author_facet "Ghane T
Kebriaezadeh A
Azizi E
Dehpour AR
Ostad SN "
author_sort "Ghane T
title The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study
title_short The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study
title_full The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study
title_fullStr The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study
title_full_unstemmed The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study
title_sort effect of lead acetate on the nitric oxide system in the rat hippocampal cells: an in-vitro study
publisher Tehran University of Medical Sciences
series Acta Medica Iranica
issn 0044-6025
1735-9694
publishDate 2001-03-01
description The mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. In this study the effect of lead acetate on the hippocampal constitutive nitric oxide production was studied. The variation in the nitric oxide production may contribute to physiological lead neurotoxicity in vivo. Different concentrations of lead acetate (10-9 to 10-6 M), wre added to cultures of hippocampal pyramidal cell obtained from one-day newborn rats. Sodium acetate was used as control. In this range of stuy viability of cells did not alter when it was compared to control (P
topic Pyramidal cell
Chronic toxicity
Rat hippocampal cells
url https://acta.tums.ac.ir/index.php/acta/article/view/2340
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