Evaluation of acetylation and methylation in oral rinse of patients with head and neck cancer history exposed to valproic acid
Abstract Evaluate the biological action of valproic acid in the acetylation of histones and in the methylation of tumor suppressor genes via oral rinse in patients with a previous history of head and neck squamous cell carcinoma (HNSCC). Forty-two active or former smokers were included in this rando...
Main Authors: | Ricardo Ribeiro Gama, Lidia Maria Rebolho Batista Arantes, Bruna Pereira Sorroche, Pedro De Marchi, Matias Eliseo Melendez, Raiany Santos Carvalho, Marcos Alves de Lima, André Luiz Vettore, André Lopes Carvalho |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-95845-3 |
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