A novel, rapid (within hours) culture-free diagnostic method for detecting live Mycobacterium tuberculosis with high sensitivity

A novel, rapid (within hours) culture-free diagnostic method for detecting live Mycobacterium tuberculosis with high sensitivity

Background: Nucleic acid amplification tests (NAATs) are widely used to diagnose tuberculosis (TB), but cannot discriminate live bacilli from dead bacilli. Live bacilli can be isolated by culture methods, but this is time-consuming. We developed a de novo TB diagnostic method that detects only live...

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Bibliographic Details
Main Authors:	Wen-Hung Wang, Rikiya Takeuchi, Shu-Huei Jain, Yong-Huang Jiang, Sonoko Watanuki, Yoshiharu Ohtaki, Kazunari Nakaishi, Satoshi Watabe, Po-Liang Lu, Etsuro Ito
Format:	Article
Language:	English
Published:	Elsevier 2020-10-01
Series:	EBioMedicine
Subjects:	Mycobacterium tuberculosis ELISA thio-NAD cycling MPT64 live bacilli detection
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396420303832

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