Down-regulation of microRNA-203-3p initiates type 2 pathology during schistosome infection via elevation of interleukin-33.
The type 2 immune response is the central mechanism of disease progression in schistosomiasis, but the signals that induce it after infection remain elusive. Aberrant microRNA (miRNA) expression is a hallmark of human diseases including schistosomiasis, and targeting the deregulated miRNA can mitiga...
Main Authors: | Xing He, Jun Xie, Yange Wang, Xiaobin Fan, Qin Su, Yue Sun, Nanhang Lei, Dongmei Zhang, Guangping Gao, Weiqing Pan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-03-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC5875897?pdf=render |
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