Reversal agents for NOACs: Connecting the dots
Objective: The objective of this review is to provide an overview on the current development of the specific reversal agents for Non-vitamin K Oral Anticoagulants (NOACs). Methods: We conducted a systematic literature search strategy to identify potential studies on Medline, Embase, and the Cochrane...
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doaj-a1defcaff91842e088dc133c7ec01b5f2020-11-25T00:06:42ZengElsevierIndian Heart Journal0019-48322016-07-0168455956310.1016/j.ihj.2015.11.023Reversal agents for NOACs: Connecting the dotsJamshed Dalal0Abhay Bhave1Gaurav Chaudhry2Prashant Rana3Director, Centre for Cardiac Sciences, Kokilaben Dhirubhai Ambani Hospital, Rao Saheb Achutrao Patwardhan Marg, Four Bunglows, Andheri (W), Mumbai 400053, IndiaHon. Consultant Haematologist, Lilavati Hospital and Research Centre, Mumbai, IndiaSenior Manager Medical Affairs, Boehringer Ingelheim India Pvt. Ltd, IndiaManager Medical Services, Boehringer Ingelheim India Pvt. Ltd, IndiaObjective: The objective of this review is to provide an overview on the current development of the specific reversal agents for Non-vitamin K Oral Anticoagulants (NOACs). Methods: We conducted a systematic literature search strategy to identify potential studies on Medline, Embase, and the Cochrane register. Conclusions: These new reversal agents for NOACs, will help address the unmet need for the management of major or life threatening bleeds, and the management of emergency surgical procedures in patients taking NOACs. It will increase confidence in the use of NOACs; thereby extending treatment to a wider range of patients.http://www.sciencedirect.com/science/article/pii/S0019483215008810SPAFNOACsReversal agentsIdarucizumabAdexanet alfa |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jamshed Dalal Abhay Bhave Gaurav Chaudhry Prashant Rana |
spellingShingle |
Jamshed Dalal Abhay Bhave Gaurav Chaudhry Prashant Rana Reversal agents for NOACs: Connecting the dots Indian Heart Journal SPAF NOACs Reversal agents Idarucizumab Adexanet alfa |
author_facet |
Jamshed Dalal Abhay Bhave Gaurav Chaudhry Prashant Rana |
author_sort |
Jamshed Dalal |
title |
Reversal agents for NOACs: Connecting the dots |
title_short |
Reversal agents for NOACs: Connecting the dots |
title_full |
Reversal agents for NOACs: Connecting the dots |
title_fullStr |
Reversal agents for NOACs: Connecting the dots |
title_full_unstemmed |
Reversal agents for NOACs: Connecting the dots |
title_sort |
reversal agents for noacs: connecting the dots |
publisher |
Elsevier |
series |
Indian Heart Journal |
issn |
0019-4832 |
publishDate |
2016-07-01 |
description |
Objective: The objective of this review is to provide an overview on the current development of the specific reversal agents for Non-vitamin K Oral Anticoagulants (NOACs).
Methods: We conducted a systematic literature search strategy to identify potential studies on Medline, Embase, and the Cochrane register.
Conclusions: These new reversal agents for NOACs, will help address the unmet need for the management of major or life threatening bleeds, and the management of emergency surgical procedures in patients taking NOACs. It will increase confidence in the use of NOACs; thereby extending treatment to a wider range of patients. |
topic |
SPAF NOACs Reversal agents Idarucizumab Adexanet alfa |
url |
http://www.sciencedirect.com/science/article/pii/S0019483215008810 |
work_keys_str_mv |
AT jamsheddalal reversalagentsfornoacsconnectingthedots AT abhaybhave reversalagentsfornoacsconnectingthedots AT gauravchaudhry reversalagentsfornoacsconnectingthedots AT prashantrana reversalagentsfornoacsconnectingthedots |
_version_ |
1725420938228400128 |