Reversal agents for NOACs: Connecting the dots

Objective: The objective of this review is to provide an overview on the current development of the specific reversal agents for Non-vitamin K Oral Anticoagulants (NOACs). Methods: We conducted a systematic literature search strategy to identify potential studies on Medline, Embase, and the Cochrane...

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Main Authors: Jamshed Dalal, Abhay Bhave, Gaurav Chaudhry, Prashant Rana
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Indian Heart Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0019483215008810
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spelling doaj-a1defcaff91842e088dc133c7ec01b5f2020-11-25T00:06:42ZengElsevierIndian Heart Journal0019-48322016-07-0168455956310.1016/j.ihj.2015.11.023Reversal agents for NOACs: Connecting the dotsJamshed Dalal0Abhay Bhave1Gaurav Chaudhry2Prashant Rana3Director, Centre for Cardiac Sciences, Kokilaben Dhirubhai Ambani Hospital, Rao Saheb Achutrao Patwardhan Marg, Four Bunglows, Andheri (W), Mumbai 400053, IndiaHon. Consultant Haematologist, Lilavati Hospital and Research Centre, Mumbai, IndiaSenior Manager Medical Affairs, Boehringer Ingelheim India Pvt. Ltd, IndiaManager Medical Services, Boehringer Ingelheim India Pvt. Ltd, IndiaObjective: The objective of this review is to provide an overview on the current development of the specific reversal agents for Non-vitamin K Oral Anticoagulants (NOACs). Methods: We conducted a systematic literature search strategy to identify potential studies on Medline, Embase, and the Cochrane register. Conclusions: These new reversal agents for NOACs, will help address the unmet need for the management of major or life threatening bleeds, and the management of emergency surgical procedures in patients taking NOACs. It will increase confidence in the use of NOACs; thereby extending treatment to a wider range of patients.http://www.sciencedirect.com/science/article/pii/S0019483215008810SPAFNOACsReversal agentsIdarucizumabAdexanet alfa
collection DOAJ
language English
format Article
sources DOAJ
author Jamshed Dalal
Abhay Bhave
Gaurav Chaudhry
Prashant Rana
spellingShingle Jamshed Dalal
Abhay Bhave
Gaurav Chaudhry
Prashant Rana
Reversal agents for NOACs: Connecting the dots
Indian Heart Journal
SPAF
NOACs
Reversal agents
Idarucizumab
Adexanet alfa
author_facet Jamshed Dalal
Abhay Bhave
Gaurav Chaudhry
Prashant Rana
author_sort Jamshed Dalal
title Reversal agents for NOACs: Connecting the dots
title_short Reversal agents for NOACs: Connecting the dots
title_full Reversal agents for NOACs: Connecting the dots
title_fullStr Reversal agents for NOACs: Connecting the dots
title_full_unstemmed Reversal agents for NOACs: Connecting the dots
title_sort reversal agents for noacs: connecting the dots
publisher Elsevier
series Indian Heart Journal
issn 0019-4832
publishDate 2016-07-01
description Objective: The objective of this review is to provide an overview on the current development of the specific reversal agents for Non-vitamin K Oral Anticoagulants (NOACs). Methods: We conducted a systematic literature search strategy to identify potential studies on Medline, Embase, and the Cochrane register. Conclusions: These new reversal agents for NOACs, will help address the unmet need for the management of major or life threatening bleeds, and the management of emergency surgical procedures in patients taking NOACs. It will increase confidence in the use of NOACs; thereby extending treatment to a wider range of patients.
topic SPAF
NOACs
Reversal agents
Idarucizumab
Adexanet alfa
url http://www.sciencedirect.com/science/article/pii/S0019483215008810
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