TO THE PROBLEM OF RADIATION-INDUCED CARCINOGENESIS AFTER TREATMENT OF HODGKIN’S LYMPHOMA AND ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS

TO THE PROBLEM OF RADIATION-INDUCED CARCINOGENESIS AFTER TREATMENT OF HODGKIN’S LYMPHOMA AND ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS

Twenty-six cases with secondary malignant tumors in children and adolescents receiving treatment for Hodgkin’s lymphoma and acute lymphoblastic leukemia were analyzed. In all cases the lesion had developed in an area of previous radiation treatment. The interval between the primary treatment and sec...

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Bibliographic Details
Main Authors: O. I. Scherbenko, R. A. Parkhomenko
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2016-02-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
radiation therapy
hodgkin’s lymphoma
acute lymphoblastic leukemia
radiation-induced carcinogenesis
Online Access:https://www.siboncoj.ru/jour/article/view/191
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spelling doaj-a1e1407f46f643b1b9d88df2f81f5c282021-07-28T21:02:00ZrusTomsk National Research Medical Center of the Russian Academy of SciencesSibirskij Onkologičeskij Žurnal1814-48612312-31682016-02-01046265191TO THE PROBLEM OF RADIATION-INDUCED CARCINOGENESIS AFTER TREATMENT OF HODGKIN’S LYMPHOMA AND ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTSO. I. Scherbenko0R. A. Parkhomenko1Russian Scientific Center of Roentgenoradiology, MoscowRussian Scientific Center of Roentgenoradiology, MoscowTwenty-six cases with secondary malignant tumors in children and adolescents receiving treatment for Hodgkin’s lymphoma and acute lymphoblastic leukemia were analyzed. In all cases the lesion had developed in an area of previous radiation treatment. The interval between the primary treatment and secondary cancer development was from 3 to 29 years. The radiation therapy dose was from 12 to 45 Gy. Treatment of secondary cancer was successful only in 5 patients, the remaining patients died of disease progression. The risk of developing secondary cancer should be considered when planning treatment for patients with hemoblastosis. In cases with favorable prognosis (complete remission after induction chemotherapy and other signs of favorable prognosis) it is advisable to withhold radiation therapy as the most important risk factor for cancer.https://www.siboncoj.ru/jour/article/view/191radiation therapyhodgkin’s lymphomaacute lymphoblastic leukemiaradiation-induced carcinogenesis
collection DOAJ
language Russian
format Article
sources DOAJ
author O. I. Scherbenko
R. A. Parkhomenko
spellingShingle O. I. Scherbenko
R. A. Parkhomenko
TO THE PROBLEM OF RADIATION-INDUCED CARCINOGENESIS AFTER TREATMENT OF HODGKIN’S LYMPHOMA AND ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS
Sibirskij Onkologičeskij Žurnal
radiation therapy
hodgkin’s lymphoma
acute lymphoblastic leukemia
radiation-induced carcinogenesis
author_facet O. I. Scherbenko
R. A. Parkhomenko
author_sort O. I. Scherbenko
title TO THE PROBLEM OF RADIATION-INDUCED CARCINOGENESIS AFTER TREATMENT OF HODGKIN’S LYMPHOMA AND ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS
title_short TO THE PROBLEM OF RADIATION-INDUCED CARCINOGENESIS AFTER TREATMENT OF HODGKIN’S LYMPHOMA AND ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS
title_full TO THE PROBLEM OF RADIATION-INDUCED CARCINOGENESIS AFTER TREATMENT OF HODGKIN’S LYMPHOMA AND ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS
title_fullStr TO THE PROBLEM OF RADIATION-INDUCED CARCINOGENESIS AFTER TREATMENT OF HODGKIN’S LYMPHOMA AND ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS
title_full_unstemmed TO THE PROBLEM OF RADIATION-INDUCED CARCINOGENESIS AFTER TREATMENT OF HODGKIN’S LYMPHOMA AND ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS
title_sort to the problem of radiation-induced carcinogenesis after treatment of hodgkin’s lymphoma and acute lymphoblastic leukemia in children and adolescents
publisher Tomsk National Research Medical Center of the Russian Academy of Sciences
series Sibirskij Onkologičeskij Žurnal
issn 1814-4861
2312-3168
publishDate 2016-02-01
description Twenty-six cases with secondary malignant tumors in children and adolescents receiving treatment for Hodgkin’s lymphoma and acute lymphoblastic leukemia were analyzed. In all cases the lesion had developed in an area of previous radiation treatment. The interval between the primary treatment and secondary cancer development was from 3 to 29 years. The radiation therapy dose was from 12 to 45 Gy. Treatment of secondary cancer was successful only in 5 patients, the remaining patients died of disease progression. The risk of developing secondary cancer should be considered when planning treatment for patients with hemoblastosis. In cases with favorable prognosis (complete remission after induction chemotherapy and other signs of favorable prognosis) it is advisable to withhold radiation therapy as the most important risk factor for cancer.
topic radiation therapy
hodgkin’s lymphoma
acute lymphoblastic leukemia
radiation-induced carcinogenesis
url https://www.siboncoj.ru/jour/article/view/191
work_keys_str_mv AT oischerbenko totheproblemofradiationinducedcarcinogenesisaftertreatmentofhodgkinslymphomaandacutelymphoblasticleukemiainchildrenandadolescents
AT raparkhomenko totheproblemofradiationinducedcarcinogenesisaftertreatmentofhodgkinslymphomaandacutelymphoblasticleukemiainchildrenandadolescents
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