Functional asymmetry and electron flow in the bovine respirasome

Respirasomes are macromolecular assemblies of the respiratory chain complexes I, III and IV in the inner mitochondrial membrane. We determined the structure of supercomplex I1III2IV1 from bovine heart mitochondria by cryo-EM at 9 Å resolution. Most protein-protein contacts between complex I, III and...

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Bibliographic Details
Main Authors: Joana S Sousa, Deryck J Mills, Janet Vonck, Werner Kühlbrandt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/21290

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