MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis
Osteoarthritis (OA) is a debilitating degenerative disease of the articular cartilage with a multifactorial etiology. Aging, the main risk factor for OA development, is associated with a systemic oxidative and inflammatory phenotype. Autophagy is a central housekeeping system that plays an antiaging...
Main Authors: | Stefania D’Adamo, Silvia Cetrullo, Manuela Minguzzi, Ylenia Silvestri, Rosa Maria Borzì, Flavio Flamigni |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
|
Series: | Oxidative Medicine and Cellular Longevity |
Online Access: | http://dx.doi.org/10.1155/2017/3720128 |
Similar Items
-
Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis
by: Manuela Minguzzi, et al.
Published: (2018-01-01) -
“Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300”
by: Rosa Maria Borzì, et al.
Published: (2019-03-01) -
Hydroxytyrosol prevents increase of osteoarthritis markers in human chondrocytes treated with hydrogen peroxide or growth-related oncogene α.
by: Annalisa Facchini, et al.
Published: (2014-01-01) -
Nutraceutical Activity in Osteoarthritis Biology: A Focus on the Nutrigenomic Role
by: Stefania D'Adamo, et al.
Published: (2020-05-01) -
Modulated Autophagy by MicroRNAs in Osteoarthritis Chondrocytes
by: Yinghao Yu, et al.
Published: (2019-01-01)