Vasodilator-stimulated phosphoprotein (VASP), a novel target of miR-4455, promotes gastric cancer cell proliferation, migration, and invasion, through activating the PI3K/AKT signaling pathway

Vasodilator-stimulated phosphoprotein (VASP), a novel target of miR-4455, promotes gastric cancer cell proliferation, migration, and invasion, through activating the PI3K/AKT signaling pathway

Abstract Background MicroRNAs (miRNAs) are small non-coding RNAs which play important roles in the carcinogenesis of gastric cancer (GC). Expression profiling of miRNAs in paired gastric cancer and adjacent normal gastric tissues has demonstrated that miR-4455 is down-regulated in gastric cancer tis...

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Bibliographic Details
Main Authors: Haiqun Chen, Gang Dai, Yiting Cai, Qinhao Gong, Wei Wu, Min Gao, Zhewei Fei
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Cancer Cell International
Subjects:
Gastric cancer
miR-4455
VASP
PI3K/AKT signaling pathway
Online Access:http://link.springer.com/article/10.1186/s12935-018-0573-4

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