A New Hydroxychavicol Dimer from the Roots of Piper betle

A New Hydroxychavicol Dimer from the Roots of Piper betle

A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of thes...

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Bibliographic Details
Main Authors: Huei-Yu Tu, Horng-Liang Lay, Chun-Chien Chien, Chwan-Fwu Lin, Tsong-Long Hwang
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Molecules
Subjects:
Piper betle
2-(g'-hydroxychavicol)-hydroxychavicol
hydroxychavciol
superoxide anion
elastase
neutrophils
Online Access:http://www.mdpi.com/1420-3049/18/3/2563
Description
Summary:A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.
ISSN:1420-3049

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