A New Hydroxychavicol Dimer from the Roots of Piper betle

A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of thes...

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Main Authors: Huei-Yu Tu, Horng-Liang Lay, Chun-Chien Chien, Chwan-Fwu Lin, Tsong-Long Hwang
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/3/2563
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spelling doaj-a21f7c7b63d24e638bd0629b9e7209f22020-11-25T01:39:05ZengMDPI AGMolecules1420-30492013-02-011832563257010.3390/molecules18032563A New Hydroxychavicol Dimer from the Roots of Piper betleHuei-Yu TuHorng-Liang LayChun-Chien ChienChwan-Fwu LinTsong-Long HwangA new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.http://www.mdpi.com/1420-3049/18/3/2563Piper betle2-(g'-hydroxychavicol)-hydroxychavicolhydroxychavciolsuperoxide anionelastaseneutrophils
collection DOAJ
language English
format Article
sources DOAJ
author Huei-Yu Tu
Horng-Liang Lay
Chun-Chien Chien
Chwan-Fwu Lin
Tsong-Long Hwang
spellingShingle Huei-Yu Tu
Horng-Liang Lay
Chun-Chien Chien
Chwan-Fwu Lin
Tsong-Long Hwang
A New Hydroxychavicol Dimer from the Roots of Piper betle
Molecules
Piper betle
2-(g'-hydroxychavicol)-hydroxychavicol
hydroxychavciol
superoxide anion
elastase
neutrophils
author_facet Huei-Yu Tu
Horng-Liang Lay
Chun-Chien Chien
Chwan-Fwu Lin
Tsong-Long Hwang
author_sort Huei-Yu Tu
title A New Hydroxychavicol Dimer from the Roots of Piper betle
title_short A New Hydroxychavicol Dimer from the Roots of Piper betle
title_full A New Hydroxychavicol Dimer from the Roots of Piper betle
title_fullStr A New Hydroxychavicol Dimer from the Roots of Piper betle
title_full_unstemmed A New Hydroxychavicol Dimer from the Roots of Piper betle
title_sort new hydroxychavicol dimer from the roots of piper betle
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2013-02-01
description A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.
topic Piper betle
2-(g'-hydroxychavicol)-hydroxychavicol
hydroxychavciol
superoxide anion
elastase
neutrophils
url http://www.mdpi.com/1420-3049/18/3/2563
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