Antioxidant and Neuroprotective Potential of the Brown Seaweed <i>Bifurcaria bifurcata</i> in an in vitro Parkinson’s Disease Model

Antioxidant and Neuroprotective Potential of the Brown Seaweed <i>Bifurcaria bifurcata</i> in an in vitro Parkinson’s Disease Model

<i>Bifurcaria bifurcata</i> is a marine brown seaweed mainly found on the Atlantic coast. Herein, we report the antioxidant and neuroprotective activities of seven fractions (F1⁻F7) obtained by normal phase chromatography from the <i>B. bifurcata</i> dichloromethane...

Full description

Bibliographic Details
Main Authors:	Joana Silva, Celso Alves, Rafaela Freitas, Alice Martins, Susete Pinteus, Joana Ribeiro, Helena Gaspar, Amparo Alfonso, Rui Pedrosa
Format:	Article
Language:	English
Published:	MDPI AG 2019-02-01
Series:	Marine Drugs
Subjects:	6-hydroxydopamine seaweeds SH-SY5Y cells neuroprotection mitochondrial membrane potential Caspase-3 activity eleganolone eleganonal neurodegenerative diseases
Online Access:	https://www.mdpi.com/1660-3397/17/2/85

Similar Items

Natural Approaches for Neurological Disorders—The Neuroprotective Potential of <i>Codium tomentosum</i>
by: Joana Silva, et al.
Published: (2020-11-01)

Eleganolone, a Diterpene from the French Marine Alga Bifurcaria bifurcata Inhibits Growth of the Human Pathogens Trypanosoma brucei and Plasmodium falciparum
by: Anne-Marie Rusig, et al.
Published: (2013-02-01)

Antioxidant and Antimicrobial Potential of the Bifurcaria bifurcata Epiphytic Bacteria
by: André Horta, et al.
Published: (2014-03-01)

Oxygenated Acyclic Diterpenes with Anticancer Activity from the Irish Brown Seaweed <i>Bifurcaria bifurcata</i>
by: Vangelis Smyrniotopoulos, et al.
Published: (2020-11-01)

Atividade citoprotetora da berberina, um alcalÃide isoquinolÃnico, sobre a toxicidade celular induzida pela 6-hidroxidopamina (6-OHDA) em cÃlulas SH-SY5Y.
by: Camylla Maria Carvalho Moura
Published: (2012)

Compressional-Puffing Pretreatment Enhances Neuroprotective Effects of Fucoidans from the Brown Seaweed Sargassum hemiphyllum on 6-Hydroxydopamine-Induced Apoptosis in SH-SY5Y Cells
by: Chun-Yung Huang, et al.
Published: (2017-12-01)

Density Functional Theory (DFT)-Aided Structure Elucidation of Linear Diterpenes from the Irish Brown Seaweed <i>Bifurcaria bifurcata</i>
by: Vangelis Smyrniotopoulos, et al.
Published: (2021-01-01)

Baicalein Prevents 6-Hydroxydopamine-Induced Mitochondrial Dysfunction in SH-SY5Y Cells via Inhibition of Mitochondrial Oxidation and Up-Regulation of DJ-1 Protein Expression
by: Yue-Hua Wang, et al.
Published: (2013-11-01)

Radical Depolymerization of Alginate Extracted from Moroccan Brown Seaweed <i>Bifurcaria bifurcata</i>
by: Bouissil Soukaina, et al.
Published: (2020-06-01)

Maackiain Ameliorates 6-Hydroxydopamine and <i>SNCA</i> Pathologies by Modulating the PINK1/Parkin Pathway in Models of Parkinson’s Disease in <i>Caenorhabditis elegans</i> and the SH-SY5Y Cell Line
by: Rong-Tzong Tsai, et al.
Published: (2020-06-01)

Proximate Composition and Nutritional Value of Three Macroalgae: Ascophyllum nodosum, Fucus vesiculosus and Bifurcaria bifurcata
by: José M. Lorenzo, et al.
Published: (2017-11-01)

Involvement of Mu Opioid Receptor Signaling in The Protective Effect of Opioid against 6-Hydroxydopamine-Induced SH-SY5Y Human Neuroblastoma Cells Apoptosis
by: Shahrzad Eftekhar-Vaghefi, et al.
Published: (2015-07-01)

Neuroprotective effects of seaweeds against 6-hydroxidopamine-induced cell death on an in vitro human neuroblastoma model
by: Joana Silva, et al.
Published: (2018-02-01)

Novel norbornane derivatives as potential neuroprotective agents
by: Egunlusi, Ayodeji Olatunde
Published: (2020)

Combined Effect of Caspase-Dependent and Caspase-Independent Apoptosis in the Anticancer Activity of Gold Complexes with Phosphine and Benzimidazole Derivatives
by: Lara Rouco, et al.
Published: (2021-12-01)

Highlighting the Biological Potential of the Brown Seaweed <i>Fucus spiralis</i> for Skin Applications
by: Rafaela Freitas, et al.
Published: (2020-07-01)

pH-Responsive Redox Nanoparticles Protect SH-SY5Y Cells at Lowered pH in a Cellular Model of Parkinson’s Disease
by: Monika Pichla, et al.
Published: (2021-01-01)

High antimicrobial activity of VLC isolated fractions from <i>Bifurcaria bifurcata</i>
by: Andre Horta
Published: (2014-06-01)

Genes Left Behind: Climate Change Threatens Cryptic Genetic Diversity in the Canopy-Forming Seaweed Bifurcaria bifurcata.
by: João Neiva, et al.
Published: (2015-01-01)

A Bibenzyl Component Moscatilin Mitigates Glycation-Mediated Damages in an SH-SY5Y Cell Model of Neurodegenerative Diseases through AMPK Activation and RAGE/NF-<i>κ</i>B Pathway Suppression
by: Mei Chou Lai, et al.
Published: (2020-10-01)

Neuroprotective effects of Camellia nitidissima Chi leaf extract in hydrogen peroxide‐treated human neuroblastoma cells and its molecule mechanisms
by: Lei An, et al.
Published: (2020-09-01)

Evaluation of the Anti-apoptotic and Anti-cytotoxic Effect of Epicatechin Gallate and Edaravone on SH-SY5Y Neuroblastoma Cells
by: Mohammad Shokrzadeh, et al.
Published: (2019-11-01)

Early Effects of Organophosphate Compounds on In Vitro Intracellular Signaling and Levels of Active Neurotrophin Receptors, and on In Vivo Neurotrophin Concentrations
by: Pomeroy-Black, Melinda J.
Published: (2014)

The neuroprotective effect of BSA-based nanocurcumin against 6-OHDA-induced cell death in SH-SY5Y cells
by: Roksana Sookhaklari, et al.
Published: (2019-02-01)

Validation of an In-Vitro Parkinson’s Disease Model for the Study of Neuroprotection
by: Esra Nur Yiğit, et al.
Published: (2018-12-01)

Neuroprotective Effect of Bergamot Juice in 6-OHDA-Induced SH-SY5Y Cell Death, an <i>In Vitro</i> Model of Parkinson’s Disease
by: Nadia Ferlazzo, et al.
Published: (2020-04-01)

Uncoupling Proteins : Regulation by IGF-1 and Neuroprotection during Hyperglycemia in Vitro
by: Gustafsson, Helena
Published: (2004)

Cytokinin Plant Hormones Have Neuroprotective Activity in In Vitro Models of Parkinson’s Disease
by: Gabriel Gonzalez, et al.
Published: (2021-01-01)

Cytotoxicity and antiproliferative activity of fractions isolated from <i>Fucus spiralis</i> seaweed
by: Celso Alves, et al.
Published: (2014-06-01)

Bifurcatriol, a New Antiprotozoal Acyclic Diterpene from the Brown Alga Bifurcaria bifurcata
by: Vangelis Smyrniotopoulos, et al.
Published: (2017-08-01)

Current Research on the Bioprospection of Linear Diterpenes from <i>Bifurcaria bifurcata</i>: From Extraction Methodologies to Possible Applications
by: Adriana C.S. Pais, et al.
Published: (2019-09-01)

Neuroprotective effects of Salvia aristata Aucher ex Benth. on hydrogen peroxide induced apoptosis in SH-SY5Y neuroblastoma cells
by: M. A. Esmaeili, et al.
Published: (2015-08-01)

Anticancer Activity of Lichen Extract (<i>Usnea</i> sp.) Based Synthesized Ag@ZnO Bimetallic Nanocomposite
by: Yakup Isik, et al.
Published: (2020-03-01)

The Molecular Mechanisms of Organophosphorus Compound-induced Cytotoxicity
by: Carlson, Kent Richard
Published: (2014)

Dual Delivery of bFGF- and NGF-Binding Coacervate Confers Neuroprotection by Promoting Neuronal Proliferation
by: Yanqing Wu, et al.
Published: (2018-06-01)

<i>Viburnum opulus</i> L. Fruit Extracts Protect Human Neuroblastoma SH-SY5Y Cells against Hydrogen Peroxide-Induced Cytotoxicity
by: Leyla Paşayeva, et al.
Published: (2019-12-01)

Unraveling the Lipidome and Antioxidant Activity of Native <i>Bifurcaria bifurcata</i> and Invasive <i>Sargassum muticum</i> Seaweeds: A Lipid Perspective on How Systemic Intrusion May Present an Opportunity
by: Fábio Santos, et al.
Published: (2020-07-01)

Parkinson's disease : experimental in vitro model validation and the potential role of cofilin-1 in the pathophysiological mechanisms
by: Lopes, Fernanda Martins
Published: (2017)

Parkinson's disease : experimental in vitro model validation and the potential role of cofilin-1 in the pathophysiological mechanisms
by: Lopes, Fernanda Martins
Published: (2017)

Parkinson's disease : experimental in vitro model validation and the potential role of cofilin-1 in the pathophysiological mechanisms
by: Lopes, Fernanda Martins
Published: (2017)