The human microbiome in the 21st century
Abstract The human body supports a thriving diversity of microbes which comprise a dynamic, ancillary, functional system that synergistically develops in lock-step with physiological development of its host. The human microbiome field has transitioned from cataloging this rich diversity to dissectin...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2020-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-18983-8 |
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doaj-a2497c420fa74fb3ae1168ae3a688dca2021-05-11T08:51:25ZengNature Publishing GroupNature Communications2041-17232020-10-011111310.1038/s41467-020-18983-8The human microbiome in the 21st centuryElze Rackaityte0Susan V. Lynch1Department of Biochemistry and Biophysics, University of California, San FranciscoDivision of Gastroenterology, Department of Medicine, University of California, San FranciscoAbstract The human body supports a thriving diversity of microbes which comprise a dynamic, ancillary, functional system that synergistically develops in lock-step with physiological development of its host. The human microbiome field has transitioned from cataloging this rich diversity to dissecting molecular mechanisms by which microbiomes influence human health. Early life microbiome development trains immune function. Thus, vertically, horizontally, and environmentally acquired microbes and their metabolites have the potential to shape developmental trajectories with life-long implications for health.https://doi.org/10.1038/s41467-020-18983-8 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Elze Rackaityte Susan V. Lynch |
| spellingShingle |
Elze Rackaityte Susan V. Lynch The human microbiome in the 21st century Nature Communications |
| author_facet |
Elze Rackaityte Susan V. Lynch |
| author_sort |
Elze Rackaityte |
| title |
The human microbiome in the 21st century |
| title_short |
The human microbiome in the 21st century |
| title_full |
The human microbiome in the 21st century |
| title_fullStr |
The human microbiome in the 21st century |
| title_full_unstemmed |
The human microbiome in the 21st century |
| title_sort |
human microbiome in the 21st century |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2020-10-01 |
| description |
Abstract The human body supports a thriving diversity of microbes which comprise a dynamic, ancillary, functional system that synergistically develops in lock-step with physiological development of its host. The human microbiome field has transitioned from cataloging this rich diversity to dissecting molecular mechanisms by which microbiomes influence human health. Early life microbiome development trains immune function. Thus, vertically, horizontally, and environmentally acquired microbes and their metabolites have the potential to shape developmental trajectories with life-long implications for health. |
| url |
https://doi.org/10.1038/s41467-020-18983-8 |
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