Effect of early hyperbaric oxygen therapy on serum indexes and erythrocyte glycometabolismm in patients with craniocerebral injury
Objective: To study the effect of early hyperbaric oxygen therapy on serum indexes and erythrocyte glycometabolismm in patients with craniocerebral injury. Methods: Patients with craniocerebral injury treated in our hospital between May 2013 and July 2016 were retrospectively analyzed and divided...
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| Format: | Article |
| Language: | English |
| Published: |
Editorial Board of Journal of Hainan Medical University
2017-05-01
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| Series: | Journal of Hainan Medical University |
| Subjects: | |
| Online Access: | http://www.hnykdxxb.com/PDF/201710/38.pdf |
| Summary: | Objective: To study the effect of early hyperbaric oxygen therapy on serum indexes and
erythrocyte glycometabolismm in patients with craniocerebral injury. Methods: Patients
with craniocerebral injury treated in our hospital between May 2013 and July 2016 were
retrospectively analyzed and divided into hyperbaric oxygen group and control group according
to the use of hyperbaric oxygen during treatment. 1 d, 3 d, 5 d and 7 d after treatment, serum
was collected to determine the levels of neuron and glial cell damage marker molecules, stress
molecules and hormones as well as erythrocyte glycometabolismm key enzymes. Results: 1d
after treatment, serum NGB, NSE, GFAP, S100β, SOD, GSH-PX, MDA, Cor, Ins, NE, E,
PFK, G-6PD and AR levels were not significantly different between two groups of patients; 3 d,
5 d and 7 d after treatment, serum NGB, NSE, GFAP, S100β, MDA, Cor, Ins, NE, E, G-6PD
and AR levels of hyperbaric oxygen group were significantly lower than those of control group
while SOD, GSH-PX and PFK levels were significantly higher than those of control group.
Conclusion: Early hyperbaric oxygen treatment of craniocerebral injury can reduce the neuron
and glial cell injury, and improve the stress state and erythrocyte glycometabolismm. |
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| ISSN: | 1007-1237 1007-1237 |