Generation of a human iPSC line from a patient with Leigh syndrome caused by a mutation in the MT-ATP6 gene

Generation of a human iPSC line from a patient with Leigh syndrome caused by a mutation in the MT-ATP6 gene

Human iPSC line L749.1 was generated from fibroblasts of a patient with Leigh syndrome associated with a heteroplasmic mutation in the MT-ATP6 gene. Reprogramming factors OCT4, SOX2, CMYC and KLF4 were delivered using retroviruses.

Bibliographic Details
Main Authors: Teresa Galera-Monge, Francisco Zurita-Díaz, Cristina González-Páramos, Ana Moreno-Izquierdo, Mario F. Fraga, Agustin F. Fernández, Rafael Garesse, M. Esther Gallardo
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116300241
Description
Summary:Human iPSC line L749.1 was generated from fibroblasts of a patient with Leigh syndrome associated with a heteroplasmic mutation in the MT-ATP6 gene. Reprogramming factors OCT4, SOX2, CMYC and KLF4 were delivered using retroviruses.
ISSN:1873-5061
1876-7753

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