Metabolic Fingerprinting for Identifying the Mode of Action of the Fungicide SYP-14288 on Rhizoctonia solani

Metabolic Fingerprinting for Identifying the Mode of Action of the Fungicide SYP-14288 on Rhizoctonia solani

The fungicide SYP-14288 has a high efficiency, low toxicity, and broad spectrum in inhibiting both fungi and oomycetes, but its mode of action (MoA) remains unclear on inhibiting fungi. In this study, the MoA was determined by analyzing the metabolism and respiratory activities of Rhizoctonia solani...

Full description

Bibliographic Details
Main Authors:	Li Liang, Xingkai Cheng, Tan Dai, Zhiwen Wang, Jin Li, Xueming Li, Bin Lei, Pengfei Liu, Jianjun Hao, Xili Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-12-01
Series:	Frontiers in Microbiology
Subjects:	uncoupler ATP synthase inhibitor membrane potential of mitochondria respiration inhibitor phosphorylation inhibitor
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2020.574039/full

Similar Items

Insights from the proteome profile of Phytophthora capsici in response to the novel fungicide SYP-14288
by: Meng Cai, et al.
Published: (2019-08-01)

Detection of trypsin inhibitor in seeds of Eucalyptus urophylla and its influence on the in vitro growth of the fungi Pisolithus tinctorius and Rhizoctonia solani
by: Tremacoldi Célia Regina, et al.
Published: (2002-01-01)

A Series of Isatin-Hydrazones with Cytotoxic Activity and CDK2 Kinase Inhibitory Activity: A Potential Type II ATP Competitive Inhibitor
by: Huda S. Al-Salem, et al.
Published: (2020-09-01)

The RsRlpA Effector Is a Protease Inhibitor Promoting <i>Rhizoctonia solani</i> Virulence through Suppression of the Hypersensitive Response
by: Spyridoula N. Charova, et al.
Published: (2020-10-01)

Defueling the cancer: ATP synthase as an emerging target in cancer therapy
by: Ting Wang, et al.
Published: (2021-12-01)

A gene for plant protection: expression of a bean polygalacturonase inhibitor in tobacco confers a strong resistance against Rhizoctonia solani and two oomycetes.
by: Orlando eBorras-Hidalgo, et al.
Published: (2012-12-01)

Impact of Fungicide Residues on Polymerase Chain Reaction and on Yeast Metabolism
by: Gildo Almeida da Silva, et al.

Paclobutrazol improves leaf carbon-use efficiency by increasing mesophyll conductance rate, while abscisic acid antagonizes this increased rate
by: L.J. XU, et al.
Published: (2020-06-01)

Recent Developments of Protein Kinase Inhibitors as Potential AD Therapeutics
by: Andreas eHilgeroth, et al.
Published: (2013-11-01)

The Biological Role of the ζ Subunit as Unidirectional Inhibitor of the F1FO-ATPase of Paracoccus denitrificans
by: Francisco Mendoza-Hoffmann, et al.
Published: (2018-01-01)

The affinity purification and characterization of ATP synthase complexes from mitochondria
by: Michael J. Runswick, et al.
Published: (2013-01-01)

The Function of Uncoupling Proteins in Various Tissues
by: Masoud Fereidoni, et al.
Published: (2013-08-01)

Targeting PIN1 as a Therapeutic Approach for Hepatocellular Carcinoma
by: Chi-Wai Cheng, et al.
Published: (2020-01-01)

In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2
by: Renee eVancraenenbroeck, et al.
Published: (2014-06-01)

Inhibitory Effects of Respiration Inhibitors on Aflatoxin Production
by: Shohei Sakuda, et al.
Published: (2014-03-01)

Data set of competitive and allosteric protein kinase inhibitors confirmed by X-ray crystallography
by: Huabin Hu, et al.
Published: (2021-04-01)

Hypoxia and metabolic inhibitors alter the intracellular ATP:ADP ratio and membrane potential in human coronary artery smooth muscle cells
by: Mingming Yang, et al.
Published: (2020-11-01)

Controlling the Mdm2-Mdmx-p53 Circuit
by: David L. Waning, et al.
Published: (2010-05-01)

Ligand-Independent EGFR Activation by Anchorage-Stimulated Src Promotes Cancer Cell Proliferation and Cetuximab Resistance via ErbB3 Phosphorylation
by: Masami Nozaki, et al.
Published: (2019-10-01)

Time-dependent matrix metalloproteinases and tissue inhibitor of metalloproteinases expression change in fusarium solani keratitis
by: Qian Li, et al.
Published: (2016-04-01)

Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study
by: Eleanor L. Atkinson, et al.
Published: (2021-03-01)

Studies on the action mechanism of epoxycyclohexenedione-type compounds, a new class of inhibitors of the mitochondrial ADP/ATP carrier
by: Aoyama, Ayaki
Published: (2021)

Limiting factors in ATP synthesis
by: Kramarova, Tatiana
Published: (2006)

Structural Basis of Inhibition of DCLK1 by Ruxolitinib
by: Dong Man Jang, et al.
Published: (2021-08-01)

Transcriptome analysis of fungicide-responsive gene expression profiles in two Penicillium italicum strains with different response to the sterol demethylation inhibitor (DMI) fungicide prochloraz
by: Tingfu Zhang, et al.
Published: (2020-02-01)

Peptide and peptide-inspired checkpoint inhibitors: Protein fragments to cancer immunotherapy
by: Pottayil G. Sasikumar, et al.
Published: (2020-12-01)

Simvastatin profoundly impairs energy metabolism in primary human muscle cells
by: Selina Mäkinen, et al.
Published: (2020-12-01)

Phosphorylation of Endothelin-Converting Enzyme-1c at Serines 18 and 20 by CK2 Promotes Aggressiveness Traits in Colorectal Cancer Cells
by: Pablo Pérez-Moreno, et al.
Published: (2020-07-01)

LRRK2 Kinase Activity and Biology are Not Uniformly Predicted by its Autophosphorylation and Cellular Phosphorylation Site Status
by: April eReynolds, et al.
Published: (2014-06-01)

Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?
by: Yotis A. Senis, et al.
Published: (2018-03-01)

Broad-Spectrum Coronavirus Fusion Inhibitors to Combat COVID-19 and Other Emerging Coronavirus Diseases
by: Xinling Wang, et al.
Published: (2020-05-01)

Targeting β-Catenin Signaling by Natural Products for Cancer Prevention and Therapy
by: Wen-Kai Yu, et al.
Published: (2020-06-01)

Mitochondrial neuronal uncoupling proteins: a target for potential disease-modification in Parkinson's disease
by: Ho Philip WL, et al.
Published: (2012-01-01)

Cyclin-Dependent Kinase Inhibitors as Marketed Anticancer Drugs: Where Are We Now? A Short Survey
by: Gaëlle Mariaule, et al.
Published: (2014-09-01)

ATP gatekeeper of Plasmodium protein kinase may provide the opportunity to develop selective antimalarial drugs with multiple targets
by: Fauze Mahmud, et al.
Published: (2020-01-01)

A One-Step Extraction and Luminescence Assay for Quantifying Glucose and ATP Levels in Cultured HepG2 Cells
by: Rita Csepregi, et al.
Published: (2018-09-01)

Modulation of TGF‐β Receptor 1 signalling in Live Cells
by: Driscoll, Brandon
Published: (2009)

Modulation of TGF‐β Receptor 1 signalling in Live Cells
by: Driscoll, Brandon
Published: (2009)

The nitric oxide‐cyclic guanosine monophosphate pathway inhibits the bladder ATP release in response to a physiological or pathological stimulus
by: Eriko Okuyama, et al.
Published: (2021-07-01)

Bowman-Birk Inhibitors: Insights into Family of Multifunctional Proteins and Peptides with Potential Therapeutical Applications
by: Agata Gitlin-Domagalska, et al.
Published: (2020-11-01)